3 documents found, page 1 of 1
Modulatory activity of brazilian red propolis on chemically induced dermal carc...
Pinheiro,Kariny Souza; Ribeiro,Danielle Rodrigues; Alves,Angela Valéria Farias; Pereira-Filho,Rose Nely; Oliveira,Clauberto Rodrigues dePURPOSE:To evaluate modulatory effects of a hydroalcoholic extract of Brazilian red propolis (HERP) on dermal carcinogenesis using a murine model.METHODS: The HERP was used at concentrations of 10, 50 and 100 mg/kg (PROP10, PROP50 and PROP100, respectively) to modulate dermal carcinogenesis induced by the application of 9,10-dimetil-1,2-benzatraceno (DMBA) on the backs of animals.RESULTS:The chemical compounds ...
Immunohistochemical profile of stromal constituents and lymphoid cells over the...
Almeida,Bernadeth Moda de; Nascimento,Marismar Fernandes do; Pereira-Filho,Rose Nely; Melo,Genecy Calado de; Santos,José Cleveilton dosPURPOSE:To assess the evolution profile of the immunohistochemical expression of stromal constituents over the time-course of wound healing in a murine model.METHODS: Surgical wounds were performed in the back of 24 Wistar rats. After three, seven, 14 and 21 days, six rats were euthanized and the wounded histologically processed to assess the immunohistochemical expression of CD3, CD20, CD31, α-SMA and type-I c...
Evaluation of wound healing activity of atranorin, a lichen secondary metabolit...
Barreto,Rosana S. S.; Albuquerque-Júnior,Ricardo L. C.; Pereira-Filho,Rose Nely; Quintans,Jullyana S. S.; Barreto,André S.; DeSantana,Josimari M.The aim of this study was to investigate the wound healing activity of atranorin cream (Patent requested) on excision wounds. Seventy-two male rats were anesthetized and an excisional wound was performed. Then the rats were randomly assigned into three groups: untreated control group; atranorin 1 (group treated with 1% AT ointment); and atranorin 5 (group treated with 5% AT ointment). Six animals of each group ...