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Seroprevalence of Protective Antibodies Against Influenza and the Reduction of ...

Guiomar, R; Pereira da Silva, S; Costa, I; Conde, P; Cristóvão, P; Rodrigues, AP; Fernandes, A; Dias, AP; Couto, AR; Ramos, A; Moita, C; Rodrigues, C

Background: Seroepidemiological studies provide estimates of population-level immunity, prevalence/incidence of infections, and evaluation of vaccination programs. We assessed the seroprevalence of protective antibodies against influenza and evaluated the correlation of seroprevalence with the cumulative annual influenza incidence rate. Methods: We conducted an annual repeated cross-sectional seroepidemiologica...


Cross-Protection to New Drifted Influenza A(H3) Viruses and Prevalence of Prote...

Guiomar, R; Pereira da Silva, S; Conde, P; Cristóvão, P; Maia, AC; Pechirra, P; Rodrigues, AP; Nunes, B; Milho, L; Coelho, AP; Fernandes, A; Caseiro, P

INTRODUCTION: Immune profile for influenza viruses is highly changeable over time. Serological studies can assess the prevalence of influenza, estimate the risk of infection, highlight asymptomatic infection rate and can also provide data on vaccine coverage. The aims of the study were to evaluate pre-existing cross-protection against influenza A(H3) drift viruses and to assess influenza immunity in the Portugu...


Detection of the protease codon 35 amino acid insertion in sequences from treat...

Pereira-Vaz, J; Duque, V; Trindade, L; Saraiva da Cunha, JG; Meliço-Silvestre, A

BACKGROUND: Amino acids insertions in the protease (PR) coding region have been reported in protease inhibitors (PIs) treatment-naïve and experienced HIV-1 infected individuals ranging from 0.1% to 4.55% and have been rarely found in non-B HIV-1 subtype strains. OBJECTIVES: To investigate the presence of amino acid insertions in the PR coding region in sequences from treatment-naïve HIV-1 infected individuals i...


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