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Global impact of fixed-dose combination therapies on cardiovascular mortality a...

Watkins, David A.; Pickersgill, Sarah; Flood, David; Gaziano, Thomas A.; Huffman, Mark D.; Islam, Shofiqul; Joseph, Philip; Perel, Pablo

Background: Uptake of drugs for primary and secondary prevention of cardiovascular disease is low in many countries. Single-pill combination (SPC) therapies consisting of a statin and 1 or more antihypertensive drugs, with or without aspirin, can reduce rates of fatal and nonfatal cardiovascular disease, but their use is currently limited. Objectives: The authors modeled the potential impact of widespread adopt...


Clearing the air to address pollution’s cardiovascular health crisis

Miller, Mark R.; Di Cesare, Mariachiara; Rahimzadeh, Shadi; Adeoye, Marvellous; Perel, Pablo; Taylor, Sean; Shrikhande, Shreya

Air pollution is a critical global health issue that significantly impacts cardiovascular health. The air pollutant PM2.5 (particulate matter with a diameter of 2.5 micrometres or less) has been positioned as a leading environmental risk factor for morbidity and mortality, especially from cardiovascular diseases (CVDs). Using data from the World Health Organization (WHO), Global Health Observatory, and the Unit...


The heart of the world

Di Cesare, Mariachiara; Perel, Pablo; Taylor, Sean; Kabudula, Chodziwadziwa; Bixby, Honor; Gaziano, Thomas A.; McGhie, Diana Vaca; Mwangi, Jeremiah

Cardiovascular diseases (CVDs) are the leading cause of mortality globally. Of the 20.5 million CVD-related deaths in 2021, approximately 80% occurred in low- and middleincome countries. Using data from the Global Burden of Disease Study, NCD Risk Factor Collaboration, NCD Countdown initiative, WHO Global Health Observatory, and WHO Global Health Expenditure database, we present the burden of CVDs, associated r...


Cardiovascular risk factors and clinical outcomes among patients hospitalized w...

Prabhakaran, Dorairaj; Singh, Kavita; Kondal, Dimple; Raspail, Lana; Mohan, Bishav; Kato, Toru; Sarrafzadegan, Nizal; Talukder, Shamim Hayder

Background and aims: Limited data exist on the cardiovascular manifestations and risk factors in people hospitalized with COVID-19 from low- and middle-income countries. This study aims to describe cardiovascular risk factors, clinical manifestations, and outcomes among patients hospitalized with COVID-19 in low, lower-middle, uppermiddle- and high-income countries (LIC, LMIC, UMIC, HIC). Methods: Through a pro...


World Heart Federation roadmap for digital health in cardiology

Tromp, Jasper; Jindal, Devraj; Redfern, Julie; Bhatt, Ami; Séverin, Tania; Banerjee, Amitava; Ge, Junbo; Itchhaporia, Dipti; Jaarsma, Tiny

More than 500 million people worldwide live with cardiovascular disease (CVD). Health systems today face fundamental challenges in delivering optimal care due to ageing populations, healthcare workforce constraints, financing, availability and affordability of CVD medicine, and service delivery. Digital health technologies can help address these challenges. They may be a tool to reach Sustainable Development Go...


The World Heart Federation global study on COVID-19 and cardiovascular disease

Sliwa, Karen; Singh, Kavita; Raspail, Lana; Ojji, Dike; Lam, Carolyn S.P.; Thienemann, Friedrich; Ge, Junbo; Banerjee, Amitava; Newby, L. Kristin

Background: The emergence of novel coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), has presented an unprecedented global challenge for the healthcare community. The ability of SARS-CoV-2 to get transmitted during the asymptomatic phase, and its high infectivity have led to the rapid transmission of COVID-19 beyond geographic regions facilitated by...


World Heart Federation Roadmap for Hypertension : a 2021 update

Jeemon, Panniyammakal; Séverin, Tania; Amodeo, Celso; Balabanova, Dina; Campbell, Norm R. C.; Gaita, Dan; Kario, Kazuomi; Khan, Taskeen; Melifonwu, Rita

The World Heart Federation (WHF) Roadmap series covers a large range of cardiovascular conditions. These Roadmaps identify potential roadblocks and their solutions to improve the prevention, detection and management of cardiovascular diseases and provide a generic global framework available for local adaptation. A first Roadmap on raised blood pressure was published in 2015. Since then, advances in hypertension...


World Heart Federation roadmap on atrial fibrillation : a 2020 update

Freedman, Ben; Hindricks, Gerhard; Banerjee, Amitava; Baranchuk, Adrian; Ching, Chi Keong; Du, Xin; Fitzsimons, Donna; Healey, Jeff S.; Ikeda, Takanori

The World Heart Federation (WHF) commenced a Roadmap initiative in 2015 to reduce the global burden of cardiovascular disease and resultant burgeoning of healthcare costs. Roadmaps provide a blueprint for implementation of priority solutions for the principal cardiovascular diseases leading to death and disability. Atrial fibrillation (AF) is one of these conditions and is an increasing problem due to ageing of...


COVID-19: Implications for People with Chagas Disease

Zaidel, Ezequiel; Forsyth, Colin; Novick, Gabriel; Marcus, Rachel; Ribeiro, Antonio Luiz; Pinazo, Maria Jesus; Morillo, Carlos; Echeverria, Luis Eduardo

As the global COVID-19 pandemic advances, it increasingly impacts the vulnerable populations who already bear a heavy burden of neglected tropical diseases. Chagas disease (CD), a neglected parasitic infection, is of particular concern because of its potential to cause cardiac, gastrointestinal, and other complications which could increase susceptibility to COVID-19. The over one million people worldwide with c...

Date: 2020   |   Origin: Oasisbr

COVID-19 : implications for people with Chagas disease

Zaidel, Ezequiel José; Forsyth, Colin J.; Novick, Gabriel; Marcus, Rachel; Ribeiro, Antonio Luiz P.; Pinazo, Maria-Jesus; Morillo, Carlos A.

As the global COVID-19 pandemic advances, it increasingly impacts those vulnerable populations who already bear a heavy burden of neglected tropical disease. Chagas disease (CD), a neglected parasitic infection, is of particular concern because of its potential to cause cardiac, gastrointestinal, and other complications which could increase susceptibility to COVID-19. The over one million people worldwide with ...


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