16 documents found, page 1 of 2

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Implementing an Influenza Vaccine Effectiveness Study in a Hospital Context in ...

Machado, Ausenda; Gomez, Verónica; Panarra, António; Poças, Jose; Corte-Real, Rita; Peres, Maria João; Nunes, Baltazar

Introduction: The project ‘Integrated Monitoring of Vaccines in Europe’ aimed to measure seasonal influenza vaccine effectiveness against hospitalised adults, aged 65 years and over, with influenza. We describe the protocol implementation in Portugal.Material and Methods: We implemented a test-negative design, targeting community-dwelling patients aged 65 years old and over hospitalised with severe acute respir...

Date: 2021   |   Origin: Acta Médica Portuguesa

Implementing an Influenza Vaccine Effectiveness Study in a Hospital Context in ...

Machado, Ausenda; Gomez, Verónica; Panarra, António; Poças, Jose; Corte-Real, Rita; Peres, Maria João; Nunes, Baltazar; EVA Hospital Group

Introduction: The project ‘Integrated Monitoring of Vaccines in Europe’ aimed to measure seasonal influenza vaccine effectiveness against hospitalised adults, aged 65 years and over, with influenza. We describe the protocol implementation in Portugal. Material and Methods: We implemented a test-negative design, targeting community-dwelling patients aged 65 years old and over hospitalised with severe acute respi...


Epidemiology and genetic variability of respiratory syncytial virus in Portugal...

Sáez-López, Emma; Cristóvão, Paula; Costa, Inês; Pechirra, Pedro; Conde, Patrícia; Guiomar, Raquel; Peres, Maria João; Viseu, Regina; Lopes, Paulo

Respiratory syncytial virus (RSV) is associated with substantial morbidity and mortality since it is a predominant viral agent causing respiratory tract infections in infants, young children and the elderly. Considering the availability of the RSV vaccines in the coming years, molecular understanding in RSV is necessary.


Epidemiology and genetic variability of respiratory syncytial virus in Portugal...

Sáez-López, Emma; Cristóvão, Paula; Costa, Inês; Pechirra, Pedro; Conde, Patrícia; Guiomar, Raquel; Peres, Maria João; Viseu, Regina; Lopes, Paulo

Introduction: Respiratory syncytial virus (RSV) is associated with substantial morbidity and mortality since it is a predominant viral agent causing respiratory tract infections in infants, young children and the elderly. Considering the availability of the RSV vaccines in the coming years, molecular understanding in RSV is necessary. Objective: The objective of the present study was to describe RSV epidemiolog...


Severe RSV infections in children and elderly during 2017/2018 winter season

Guiomar, Raquel; Pechirra, Pedro; Costa, Inês; Cristóvão, Paula; Conde, Patrícia; Nunes, Baltazar; Rodrigues, Ana Paula; Côrte-Real, Rita

Background: Respiratory syncytial virus (RSV) is one of the most frequent and important respiratory viral agent that causes respiratory infection complications in younger children and elderly. RSV has an autumn / winter seasonality detected in cocirculation with influenza and other respiratory viruses. Material and Methods: During 2017/2018 season, 14 hospitals from Portugal mainland and Atlantic Island tested ...


Influenza virus type/subtype and different infection profiles by age group duri...

Guiomar, Raquel; Pechirra, Pedro; Cristóvão, Paula; Costa, Inês; Conde, Patrícia; Côrte-Real, Rita; Branquinho, Paula; Garcia, David; Conde, Sílvia

Background: Influenza has a major impact in hospitalization during each influenza season. We analysed the influenza type/subtype distribution by age group and medical care wards (ambulatory, hospital, intensive care unit). Material and Methods: During 2017/2018 season, 14 hospitals from Portugal mainland and Atlantic Island (Azores and Madeira) reported to the National Influenza Centre 13747 cases of respirator...


Cross-protection to new drifted influenza A(H3) viruses and prevalence of prote...

Guiomar, Raquel; Pereira da Silva, Susana; Conde, Patrícia; Cristóvão, Paula; Maia, Ana Carina; Pechirra, Pedro; Rodrigues, Ana Paula; Nunes, Baltazar

Introduction: Immune profile for influenza viruses is highly changeable over time. Serological studies can assess the prevalence of influenza, estimate the risk of infection, highlight asymptomatic infection rate and can also provide data on vaccine coverage. The aims of the study were to evaluate pre-existing cross-protection against influenza A(H3) drift viruses and to assess influenza immunity in the Portugu...


Avaliação da exequibilidade de um estudo de efetividade da vacina antigripal co...

Gómez, Verónica; Gomes, Victor; Poças, José; Côrte-Real, Rita; Peres, Maria João; Rodrigues, Ana Paula; Machado, Ausenda; Nunes, Baltazar

Introdução/Objetivo do trabalho: O projeto EVA Hospital é a componente portuguesa do estudo multicêntrico europeu I-MOVE+ (Integrated Monitoring of Vaccines Effects in Europe) e pretende obter estimativas da efetividade da vacina antigripal (EVA) contra gripe confirmada laboratorialmente em doentes com 65 e mais anos hospitalizados com infeção respiratória aguda grave (SARI). Na época 2015-16 este estudo teve c...


Cross-protection to new drifted influenza A(H3) viruses and prevalence of prote...

Guiomar, Raquel; Pereira da Silva, Susana; Conde, Patrícia; Cristóvão, Paula; Maia, Ana Carina; Pechirra, Pedro; Rodrigues, Ana Paula; Nunes, Baltazar

Introduction: Immune profile for influenza viruses is highly changeable over time. Serological studies can assess the prevalence of influenza, estimate the risk of infection, highlight asymptomatic infection rate and can also provide data on vaccine coverage. The aims of the study were to evaluate pre-existing cross-protection against influenza A(H3) drift viruses and to assess influenza immunity in the Portugu...


Influenza seroprotection correlates with predominant circulating viruses during...

Guiomar, Raquel; Cristóvão, Paula; Conde, Patrícia; Costa, Inês; Pechirra, Pedro; Rodrigues, Ana Paula; Pereira da Silva, Susana; Nunes, Baltazar

BACKGROUND: Population immune profile for influenza is highly affected by circulating influenza viruses, thus changing the risk of infection for influenza. This study aims to assess influenza immunity in the Portuguese population by age groups, during 2014 and 2015 and establish a relationship between seroprotection and circulating influenza viruses in 2014/15 and 2015/16 seasons. METHODS: Two cross-sectional s...


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