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Aerobic exercise training induces an anti-apoptotic milieu in myocardial tissue

Santana,Eduardo Tadeu; Serra,Andrey Jorge; Silva Junior,José Antonio; Bocalini,Danilo Sales; Barauna,Valério Garrone; Krieger,José Eduardo

This study evaluated modulators of apoptosis in the myocardium of rats subjected to exercise training. Rats were assigned to non-trained and exercise-trained groups, respectively. The animals ran for 1 h per day, 6 times per week and, for a total of 13 weeks. The left ventricle was processed for analysis of gene and protein anti- (Bcl-2, c-IAP1, c-IAP2, Survivin, ILK, Akt and pAkt) and pro- (Bad) apoptotic expr...

Date: 2014 | Origin: Oasisbr

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