Encontrados 2 documentos, a visualizar página 1 de 1
Antibacterial, antibiofilm and cytotoxic activities of Terminalia fagifolia Mar...
Araujo, Alyne Rodrigues de; Quelemes, Patrick Veras; Perfeito, Márcia Luana Gomes; Lima, Luiza Ianny de; Sá, Melka Coêlho; Nunes, Paulo Humberto MoreiraBackground: The methicillin resistance of bacteria from the genus Staphylococcus and its ability to form biofilms are important factors in pathogenesis of these microorganisms. Thus, the search for new antimicrobials agents, especially from plants, has been intensified. In this context, Terminalia species have been the subject of research for many pharmacological activities. In this study we evaluated the antib...
Characterization and Biological Activities of Ocellatin Peptides from the Skin ...
Marani, Mariela Mirta; Dourado, Flávio Santos; Quelemes, Patrick Veras; Araujo, Alyne Rodrigues de; Perfeito, Márcia Luana Gomes; Barbosa, Eder AlvesEight new peptides were isolated from the skin secretion of the frog Leptodactylus pustulatus and their amino acid sequences determined by de novo sequencing and by cDNA cloning. Structural similarities between them and other antimicrobial peptides from the skin secretion of Leptodactylus genus frogs were found. Ocellatins-PT1 to -PT5 (25 amino acid residues) are amidated at the C-terminus, while ocellatins-PT6...