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Withanolides from leaves of Nicandra physalodes

Carrero, Diego A. S.; Batista, Pedro H. J.; Souza, Luciana G. S.; Pinto, Francisco C. L.; Vasconcelos, Mayron A. de; Teixeira, Edson H.

Five new withanolides, designated as 15-oxo-nicaphysalin B, 6 β ,7 α -dihydroxynicandrenone 10, 24 α ,25 β -dihydroxy-nicandrenone-2 and a mixture of the epimers 17-(1 α /1 β -methylpropanone)- nicandrenone, in addition to six known others, were isolated from the leaf acetone extract from Nicandra physalodes . The complete structures of the five new withanolides, particularly their relative stereochemistries, w...

Date: 2018   |   Origin: Oasisbr


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