13 documents found, page 1 of 2
Advancing Access to Intestinal Microbiota Transplant: Bridging the Gap Between ...
Dinis, L; Pinheiro, H; Póvoa, P; Calhau, C; Pestana, D; Marques, CClostridioides difficile is an opportunistic pathogen that can cause a range of conditions, from asymptomatic carriage to severe illness, posing a significant public health threat due to its high mortality rates and substantial healthcare costs. Traditional treatment options, including antibiotics, often fail to eradicate the infection, leading to recurrent cases that severely impact patients' lives. Intestinal...
Noncompliance to iodine supplementation recommendation is a risk factor for iod...
Matta Coelho, CM; Guimaraes, J; Bracchi, I; Xavier Moreira, NX; Pinheiro, C; Ferreira, P; Pestana, D; Barreiros Mota, IB; Cortez, A; Prucha, CPurpose After a recommendation for iodine supplementation in pregnancy has been issued in 2013 in Portugal, there were no studies covering iodine status in pregnancy in the country. The aim of this study was to assess iodine status in pregnant women in Porto region and its association with iodine supplementation. Methods A cross-sectional study was conducted at Centro Hospitalar Universitário São João, Porto, f...
Association between Elevated Iodine Intake and IQ among School Children in Port...
Carvalho, IP; Peixoto, B; Caldas, JC; Costa, A; Silva, S; Moreira, B; Almeida, A; Moreira-Rosário, A; Guerra, A; Delerue-Matos, C; Sintra, D; Pestana, DThe goal of this work was to examine whether elevated iodine intake was associated with adverse effects on IQ among school-age children in Portugal. In a representative sample of children from the north of the country, IQ percentiles by age (assessed with Raven’s Colored Progressive Matrices) were dichotomized to <50 (“below-average” IQs) and ≥50. Morning urine iodine concentrations, corrected for creatinine, w...
A Pilot Study on the Metabolic Impact of Mediterranean Diet in Type 2 Diabetes:...
Ismael, S; Silvestre, MP; Vasques, M; Araújo, JR; Morais, J; Duarte, MI; Pestana, D; Faria, A; Pereira-Leal, JB; Vaz, J; Ribeiro, P; Teixeira, DThe Mediterranean diet (MD) has been recommended for type 2 diabetes (T2D) treatment. The impact of diet in shaping the gut microbiota is well known, particularly for MD. However, the link between MD and diabetes outcome improvement is not completely clear. This study aims to evaluate the role of microbiota modulation by a nonpharmacological intervention in patients with T2D. In this 12-week single-arm pilot st...
Gut Microbiota Diversity and C-Reactive Protein Are Predictors of Disease Sever...
Moreira-Rosário, A; Marques, C; Pinheiro, H; Araújo, JR; Ribeiro, P; Rocha, R; Mota, I; Pestana, D; Ribeiro, R; Pereira, A; Sousa, MJ; Pereira-Leal, JThe risk factors for coronavirus disease 2019 (COVID-19) severity are still poorly understood. Considering the pivotal role of the gut microbiota on host immune and inflammatory functions, we investigated the association between changes in the gut microbiota composition and the clinical severity of COVID-19. We conducted a multicenter cross-sectional study prospectively enrolling 115 COVID-19 patients categoriz...
The association of milk and dairy consumption with iodine status in pregnant wo...
Ferreira, P; Pinheiro, C; Matta Coelho, C; Guimarães, J; Pereira, G; Xavier Moreira, N; Cortez, A; Bracchi, I; Pestana, D; Barreiros Mota, I; Prucha, CThe role of milk and dairy products in supplying iodine to pregnant women is unknown in Portugal. The aim of this study was to evaluate the association between milk and dairy product consumption and the iodine status of pregnant women in the IoMum cohort of the Oporto region. Pregnant women were recruited between 10 and 13 weeks of gestation, when they provided a spot urine sample and information on lifestyle a...
Iodine knowledge is associated with iodine status in Portuguese pregnant women:...
Pinheiro, C; Xavier, Moreira, N; Ferreira, P; Matta, Coelho, C; Guimarães, J; Pereira, G; Cortez, A; Bracchi, I; Pestana, D; Barreiros, Mota, ILack of knowledge about iodine has been suggested as a risk factor for iodine deficiency in pregnant women, but no studies have addressed this issue in Portugal. So, the aim of this study was to investigate iodine knowledge among Portuguese pregnant women and its association with iodine status. IoMum, a prospective observational study, included 485 pregnant women recruited at Centro Hospitalar e Universitário d...
Nutrition Education in Portuguese Medical Students
Mota, Inês Barreiros; Castela, Inês; Morais, Juliana; Anjos, Miguel; Costa, João Pedro; Dias, Marta; Fernandes, Ana; Leitão, Iara; Mohanlal, UrmilkINTRODUCTION: Nutrition has been underrepresented in the curriculum of many medical schools and therefore physicians do not feel adequately prepared to provide dietary counselling. The aim of the present study is to determine the impact of a Nutrition and Metabolism curricular unit on nutrition attitudes, knowledge and confidence on future clinical practice of medical students. MATERIAL AND METHODS: All the stu...
A review of exposure assessment methods for epidemiological studies of health e...
Hoek, G; Ranzi, A; Alimehmeti, I; Ardeleanu, ER; Arrebola, JP; Ávila, P; Candeias, C; Colles, A; Crișan, GC; Dack, S; Demeter, Z; Fazzo, L; Fierens, TBACKGROUND: this paper is based upon work from COST Action ICSHNet. Health risks related to living close to industrially contaminated sites (ICSs) are a public concern. Toxicology-based risk assessment of single contaminants is the main approach to assess health risks, but epidemiological studies which investigate the relationships between exposure and health directly in the affected population have contributed...
Effects of xenoestrogens in human M1 and M2 macrophage migration, cytokine rele...
Teixeira, D; Marques, C; Pestana, D; Faria, A; Norberto, S; Calhau, C; Monteiro, RBisphenol A (BPA), bis(2-ethylhexyl)phthalate (DEHP) and di(n-butyl)phthalate (DBP) are environmental estrogens that have been associated with a wide range of adverse health outcomes for which inflammation has also been hypothesized as a potentially involved mechanism and where macrophages play a central role. This study was carried out to evaluate if xenoestrogen (XE) treatment of classically (M1) or alternati...