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Breast Adipose Tissue's Xenobiotics and Fatty Acid Profile-A Preliminary Study ...

Sousa, Sara; Paíga, Paula; Araújo, Bárbara; Coelho, Francisca; Castela, Inês; Vasques, Miguel; Sampaio, Clara; Duarte, Marta; Correia, Ana

Countless environmental pollutants and xenobiotics, are widespread and linked to hazardous effects, including breast cancer. Due to their lipophilic properties, these accumulate in fat tissue, such as breast adipose tissue. However, little is still known about their combined effects and distribution within the breast microenvironment. Alterations in fatty acid metabolism can be a biomarker for cancer progressio...


Breast Adipose Tissue’s Xenobiotics and Fatty Acid Profile—A Preliminary Study ...

Sousa, Sara; Paíga, Paula; Araújo, Bárbara; Coelho, Francisca; Castela, Inês; Vasques, Miguel; Sampaio, Clara; Duarte, Marta; Correia, Ana

Countless environmental pollutants and xenobiotics, are widespread and linked to hazardous effects, including breast cancer. Due to their lipophilic properties, these accumulate in fat tissue, such as breast adipose tissue. However, little is still known about their combined effects and distribution within the breast microenvironment. Alterations in fatty acid metabolism can be a biomarker for cancer progressio...


Avaliação da Informação Científica no Youtube

Pestana, Diogo; Rosa, Diogo; Gomes, Inês; Machado, Inês

O YouTube é um dos sites mais populares do mundo, conhecido, não só, pelo entretenimento audiovisual, mas também por possuir vídeos com conteúdo relevante das melhores universidades do mundo. A área interdisciplinar da Ciência da Informação procura oferecer recursos para o tratamento da informação. Com o avanço das tecnologias de informação e comunicação, a Internet tornou-se a primeira fonte de procura de info...

Date: 2025   |   Origin: Cadernos Pedagógicos

Advancing Access to Intestinal Microbiota Transplant: Bridging the Gap Between ...

Dinis, Liliana; Pinheiro, Hélder; Póvoa, Pedro; Calhau, Conceição; Pestana, Diogo; Marques, Cláudia

Clostridioides difficile is an opportunistic pathogen that can cause a range of conditions, from asymptomatic carriage to severe illness, posing a significant public health threat due to its high mortality rates and substantial healthcare costs. Traditional treatment options, including antibiotics, often fail to eradicate the infection, leading to recurrent cases that severely impact patients’ lives. Intestinal...

Date: 2025   |   Origin: Acta Médica Portuguesa

Advancing Access to Intestinal Microbiota Transplant

Dinis, Liliana; Pinheiro, Helder; Povoa, Pedro; Calhau, Conceição; Pestana, Diogo; Marques, Cláudia

Clostridioides difficile is an opportunistic pathogen that can cause a range of conditions, from asymptomatic carriage to severe illness, posing a significant public health threat due to its high mortality rates and substantial healthcare costs. Traditional treatment options, including antibiotics, often fail to eradicate the infection, leading to recurrent cases that severely impact patients' lives. Intestinal...


Essential trace elements status in portuguese pregnant women and their associat...

Bracchi, Isabella; Guimarães, Juliana; Rodrigues, Catarina; Azevedo, Rui; Coelho, Cláudia Matta; Pinheiro, Cátia; Morais, Juliana; Barreiros-Mota, Inês

Cobalt (Co), copper (Cu), manganese (Mn), molybdenum (Mo), and zinc (Zn) are essential trace elements (ETEs) important in cellular chemical reactions and antioxidant defense. Ingestion of ETEs during pregnancy is crucial but their role in specific pregnancy outcomes is largely unknown. This study aimed to quantify urinary levels of these ETEs in pregnancy and to evaluate their role in pregnancy health. First tr...


Association of 3-Phenoxybenzoic Acid Exposure during Pregnancy with Maternal Ou...

Guimarães, Juliana; Bracchi, Isabella; Pinheiro, Cátia; Moreira, Nara Xavier; Coelho, Cláudia Matta; Pestana, Diogo; Prucha, Maria do Carmo

The aims of this study were to characterize the exposure of pregnant women living in Portugal to 3-phenoxybenzoic acid (3-PBA) and to evaluate the association of this exposure with maternal outcomes and newborn anthropometric measures. We also aimed to compare exposure in summer with exposure in winter. Pregnant women attending ultrasound scans from April 2018 to April 2019 at a central hospital in Porto, Portu...


Impact of brominated flame retardants on lipid metabolism: An in vitro approach

Maia, Maria Luz; Sousa, Sara; Pestana, Diogo; Faria, Ana; Teixeira, Diana; Delerue-Matos, Cristina; Domingues, Valentina; Calhau, Conceição

Brominated flame retardants (BFRs) are chemicals employed to lower the flammability of several objects. These endocrine disruptor chemicals are lipophilic and persistent in the environment. Due to these characteristics some have been restricted or banned by the European Union, and replaced by several new chemicals, the novel BFRs (NBFRs). BFRs are widely detected in human samples, such as adipose tissue and som...


Association between elevated iodine intake and IQ among school children in Port...

Carvalho, Irene P.; Peixoto, Bruno; Caldas, José Carlos; Costa, Ana; Silva, Sofia; Moreira, Bárbara; Almeida, Agostinho; Moreira-Rosário, André

The goal of this work was to examine whether elevated iodine intake was associated with adverse effects on IQ among school-age children in Portugal. In a representative sample of children from the north of the country, IQ percentiles by age (assessed with Raven’s Colored Progressive Matrices) were dichotomized to <50 (“below-average” IQs) and ≥50. Morning urine iodine concentrations, corrected for creatinine, w...


Association between Elevated Iodine Intake and IQ among School Children in Port...

Carvalho, Irene P.; Peixoto, Bruno; Caldas, José Carlos; Costa, Ana; Silva, Sofia; Moreira, Bárbara; Almeida, Agostinho; Moreira-Rosário, André

The goal of this work was to examine whether elevated iodine intake was associated with adverse effects on IQ among school-age children in Portugal. In a representative sample of children from the north of the country, IQ percentiles by age (assessed with Raven’s Colored Progressive Matrices) were dichotomized to <50 (“below-average” IQs) and ≥50. Morning urine iodine concentrations, corrected for creatinine, w...


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