18 documents found, page 1 of 2
Lessons from Four Decades of Systemic Amyloidosis with Renal Involvement
Oliveira-Silva, C; Marques, N; Pinho, A; Poínhos, Rui; Bergantim, R; Nunes, AT; Sampaio, S; Rodrigues-Pereira, P; Silva, R; Praça, A; Frazão, JBackground: Apart from ATTR amyloidosis, the epidemiology and outcomes of the most common subtypes of systemic amyloidosis in Portugal remain primarily unknown. Methods: This retrospective cohort study evaluated patients with renal biopsy-proven amyloidosis, diagnosed from January 1978 to December 2019. Follow-up started at kidney disease presentation and ended at death or August 2020. Clinical presentation, su...
Syphilitic Hepatitis: a Rare Complication of Secondary Syphilis. A Case Report
Caldeira, M; João, AL; Pestana, M; Canha, I; Simões, G; Fernandes, CSyphilis is a sexually transmitted disease caused by Treponema pallidum, progressing through active and latent stages if left untreated. Hepatic involvement can occur in secondary syphilis, but this is an uncommon complication, with few published case reports. A 34-year-old man without significant medical history was admitted to the gastroenterology department with a 2-week history of unexplained jaundice and a...
Teledermatology and the COVID-19 Pandemic: Experience from a Portuguese Center
Santos-Coelho, M; Barbosa, J; Pestana, M; Caldeira, M; Paiva Lopes, MJ; Cabete, JIntroduction: In order to maintain assistential activity while ensuring social distancing and mobility restrictions imposed during the COVID-19 pandemic, the Dermatovenereology Department of Hospital de Santo António dos Capuchos implemented an asynchronous teledermatology platform based on e-mail and smartphones. This study aims to evaluate its application to urgent outpatient and inpatient consultations while...
Circulating renalase as predictor of renal and cardiovascular outcomes in pre-d...
Cerqueira, A; Quelhas-Santos, J; Ferreira, I; Sampaio, S; Relvas, M; Marques, N; Dias, CC; Pestana, MChronic kidney disease (CKD) is an independent risk factor for adverse cardiovascular and cerebrovascular events (MACCEs), and mortality since the earlier stages. Therefore, it is critical to identify the link between CKD and cardiovascular risk (CVR) through early and reliable biomarkers. Acknowledging that CKD and CKD progression are associated with increased sympathetic tone, which is implicated in CVR, and ...
Viral Clearance and Serological Response to SARS-CoV-2 in Kidney Transplant Rec...
Silvano, J; Ferreira, F; Bustorff, M; Nunes, AT; Tavares, I; Sobrinho Simões, J; Ramos, A; Cardoso, MJ; Sampaio, S; Pestana, MObjectives Knowledge about the impact of coronavirus disease 2019 (COVID-19) on kidney transplant recipients (KTRs) concerning viral shedding and humoral immune response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is limited. The aim of this study is to analyze viral dynamics and the antibody response to SARS-CoV-2 in KTRs with COVID-19 and study their association with clinical data. Ma...
Endothelial dysfunction is associated with cerebrovascular events in pre-dialys...
Cerqueira, A; Quelhas-Santos, J; Sampaio, S; Ferreira, I; Relvas, M; Marques, N; Dias, CC; Pestana, MBackground: Patients with chronic kidney disease (CKD) have markedly increased rates of end stage renal disease, major adverse cardiovascular/cerebrovascular events (MACCEs), and mortality. Endothelial dysfunction (ED) is an early marker of atherosclerosis that is emerging as an increasingly important non-traditional cardiovascular risk factor in CKD. There is a lack of clinical studies examining the associatio...
Exposure of smaller and oxidized graphene on polyurethane surface improves its ...
Borges, I; Henriques, PC; Gomes, RN; Pinto, AM; Pestana, M; Magalhães, FD; Gonçalves, ICCatheter-related infections are a common worldwide health problem, highlighting the need for antimicrobial catheters. Here, antibacterial potential of graphene nanoplatelets (GNP) incorporated in the commonly used polymer for catheter manufacture—polyurethane (PU)—is investigated. Two strategies are explored: melt-blending, producing a composite, and dip coating, where a composite layer is deposited on top of P...
Peritoneal microbiome in end-stage renal disease patients and the impact of per...
Simões-Silva, L; Araujo, R; Pestana, M; Isabel, SS; Sampaio-Maia, BFactors influencing the occurrence of peritoneal dialysis (PD)-related infections are still far from fully understood. Recent studies described the existence of specific microbiomes in body sites previously considered microbiome-free, unravelling new microbial pathways in the human body. In the present study, we analyzed the peritoneum of end-stage kidney disease (ESKD) patients to determine if they harbored a ...
Erratum: Borges, I., et al. Exposure of Smaller and Oxidized Graphene on Polyur...
Borges, I; Henriques, PC; Gomes, RN; Pinto, AM; Pestana, M; Magalhães, FD; Gonçalves, ICThe authors wish to make the following corrections to this paper [1]: Funding: This research was funded by Fundação para a Ciência e a Tecnologia (FCT) and Fundo Europeu de Desenvolvimento Regional (FEDER) for Projects POCI-01-0145-FEDER-006939, POCI-01-0145-FEDER-007274, PTDC/CTM-BIO/4033/2014, and NORTE-01-0145-FEDER-000012, and projects UID/BIM/04293/2019—i3S and UIDB/00511/2020—LEPABE, funded by national fu...
Early versus late conversion from immediate to prolonged-release tacrolimus aft...
Mendonça, L; Diniz, H; Silvano, J; Marques, S; Sampaio, S; Pestana, MIntroduction. Prolonged-release tacrolimus (PR-TAC) was associated with improved renal function after transplantation when compared to immediate-release tacrolimus (IR-TAC) although evidence is still scarce. This study aimed to compare clinical outcomes and treatment costs in patients who converted from IR-TAC to PR-TAC during the first year after renal transplantation (RT) (early converters [EC]) or after that...