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A case of lupus podocytopathy and a review of the literature

Silvano,José; Praça,Augusta; Ferreira,Inês Castro; Nunes,Ana Teresa; Rodrigues-Pereira,Pedro; Silva,Roberto Pestana; Sampaio,Susana; Pestana,Manuel

ABSTRACT Nephrotic syndrome in systemic lupus erythematosus patients with histological evidence of minimal change disease, mesangial proliferation or focal and segmental glomerulosclerosis on light microscopy, represents a distinct clinical entity - lupus podocytopathy. This entity is characterized by a diffuse foot process effacement on electron microscopy and by absence of subepithelial or subendothelial immu...

Date: 2021   |   Origin: SciELO Portugal

Chemical peritonitis associated with intraperitoneal vancomycin: A case series

Silvano,José; Pereira,Luciano; Oliveira,Ana; Beco,Ana; Relvas,Miguel; Silva,Rui; Pestana,Manuel

ABSTRACT Peritonitis is a serious complication in peritoneal dialysis, usually secondary to an infectious cause. Chemical peritonitis is rarer. No case exclusively attributed to vancomycin has been reported in the last 20 years. Data from 4 consecutive patients diagnosed with culture‑negative peritonitis following administration of intraperitoneal vancomycin between May and June 2019 were retrospectively record...

Date: 2021   |   Origin: SciELO Portugal

Heart failure in chronic kidney disease patients: a summary of non-traditional ...

Viveiros,Luísa; Pestana,Manuel

Introduction: Patients with chronic kidney disease are at higher risk of heart failure than the general population. Such increased risk is multifactorial, being partly due to a higher prevalence of traditional cardiovascular risk factors in this population and to the existence of non-traditional/chronic kidney disease-specific risk factors. Non-traditional risk factors should prompt special considerations in di...

Date: 2018   |   Origin: SciELO Portugal

Renal transplantation in patients with congenital abnormalities of the lower ur...

Marques,Sofia; Ferreira,Carlos; Sampaio,Susana; Bustorff,Manuela; Pestana,Manuel

Introduction: Renal transplantation in adults with congenital abnormalities of the lower urinary tract (CALUT) carries particular complications. Careful urologic evaluation of abnormal bladders, due to neuropathy or outlet obstruction, may indicate the need for surgical correction before transplantation. This population is also at increased risk for urinary tract infections. Purpose: We assessed the outcome of ...

Date: 2016   |   Origin: SciELO Portugal

Exit-site fungal infections: experience of a Peritoneal Dialysis Unit

Coelho,Sofia; Beco,Ana; Oliveira,Ana; Santos,Carla; Pestana,Manuel

Introduction: Exit-site infections are an important complication of peritoneal dialysis; however, very little is known about fungi-related exit-site infections. The literature is very sparse and there are virtually no studies that report it. Objective: To evaluate in retrospect the risk factors associated with exit-site fungal infection and its development. Methods: The study included all diagnosed episodes of ...

Date: 2016   |   Origin: SciELO Portugal

Endothelial function assessed by peripheral arterial tonometry is not related w...

Cerqueira,Ana; Quelhas-Santos,Janete; Pestana,Manuel

Cardiovascular (CV) diseases are the leading causes of morbidity and mortality in patients with chronic kidney disease (CKD) that encompass the mildest degrees of renal impairment. High levels of phosphate and fibroblast growth factor 23 (FGF-23) are associated with increased CV events in this population. However, differences in clinical and pathological manifestations have suggested that distinct mechanisms ma...

Date: 2015   |   Origin: SciELO Portugal

Predicting risk in CKD

Pestana,Manuel

Date: 2015   |   Origin: SciELO Portugal

Alternative vascular access for haemodialysis: a single centre experience in tr...

Barros,Francisca; Carvalho,Berta; Vaz,Raquel; Martins,Patrícia; Neto,Ricardo; Pestana,Manuel

Introduction: Vascular access for haemodialysis represents a major problem for patients undergoing this technique. The construction of fistulas or grafts is not always feasible, and a central venous catheter remains as the sole option. Exhaustion of the common sites for central venous catheter’s placement is common, which sometimes leads to new life-saving approaches. Methods: We retrospectively reviewed the ch...

Date: 2014   |   Origin: SciELO Portugal

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