2 documents found, page 1 of 1
The challenges of the expanded availability of genomic information: an agenda-s...
Borry, P; Bentzen, H; Budin-Ljøsne, I; Cornel, M; Howard, H; Feeney, O; Jackson, L; Mascalzoni, D; Mendes, A; Peterlin, B; Riso, B; Shabani, MRapid advances in microarray and sequencing technologies are making genotyping and genome sequencing more affordable and readily available. There is an expectation that genomic sequencing technologies improve personalized diagnosis and personalized drug therapy. Concurrently, provision of direct-to-consumer genetic testing by commercial providers has enabled individuals’ direct access to their genomic data. The...
Y-chromosomal diversity in Europe is clinal and influenced primarily by geograp...
Rosser, ZH; Zerjal, T; Hurles, ME; Adojaan, MA; Alavantic, D; Amorim, A; Amos, W; Armenteros, M; Arroyo, E; Barbujani, G; Beckman, L; Bertranpetit, JClinal patterns of autosomal genetic diversity within Europe have been interpreted in previous studies in terms of a Neolithic demic diffusion model for the spread of agriculture; in contrast, studies using mtDNA have traced many founding lineages to the Paleolithic and have not shown strongly clinal variation. We have used 11 human Y-chromosomal biallelic polymorphisms, defining 10 haplogroups, to analyze a sa...