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Photonic modulation of epidermal growth factor receptor halts receptor activati...
Botelho, Cláudia M.; Gonçalves, O.; Marques, R.; Thiagarajan, V.; Vorum, H.; Gomes, Andreia C; Petersen-Neves, T.Epidermal Growth Factor Receptor (EGFR) plays a key role in regulating cell survival, proliferation and migration, and its overexpression and activation has been correlated with cancer progression. Cancer therapies targeting EGFR have been applied in the clinic with some success. We show, by confocal microscopy analysis, that illumination of adenocarcinomic human alveolar basal epithelial cells (Human A549 EGFR...
Date: 2018
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Origin: RepositóriUM - Universidade do Minho