30 documents found, page 1 of 3
Microperimetry differences in macular sensitivity threshold between first and s...
Junqueira,Natacha B.; Lima,Luiz H.; Ferreira,Rodrigo B.; Garcia,Denny Marcos; Furtado,João M.; Jorge,RodrigoABSTRACT Purpose: To comparatively assess the macular sensitivity threshold of microperimetry and the fixation stability between the first (right) and second (left) tested eye of normal participants. Methods: Thirty healthy patients were randomly assigned to two groups. The participants underwent microperimetry in the fast mode and expert mode in groups I and II, respectively. Each participant underwent a singl...
Ocular sequelae of retinopathy of prematurity in Manaus, Amazonas
Ribeiro,Jefferson Augusto Santana; Carvalho,Filipe Sampaio; Viterbino,Dhielly Santos; Cohen,Jacob Moysés; Jorge,RodrigoAbstract Purpose: To evaluate the structural ocular sequelae of retinopathy of prematurity in children at risk for the disease in Manaus, Amazonas, Brazil. Methods: A prospective, cohort-type, observational study was conducted. Fifty-seven children at risk for this retinopathy, who were born in the public health system facilities, were referred for ophthalmic evaluation at a secondary eye hospital. Inclusion cr...
Clinical studies using stem cells for treatment of retinal diseases: state of t...
Cotrim,Carina Costa; Jorge,Rodrigo; Oliveira,Maria Carolina de; Pieroni,Fabiano; Messias,André M. Vieira; Siqueira,Rubens CamargoABSTRACT Degenerative retinal diseases such as retinitis pigmentosa, Stargardt’s macular dystrophy, and age-related macular degeneration are characterized by irreversible loss of vision due to direct or indirect photoreceptor damage. No effective treatments exist, but stem cell studies have shown promising results. Our aim with this review was to describe the types of stem cells that are under study, their effe...
ETDRS panretinal photocoagulation combined with intravitreal ranibizumab versus...
Barroso,Rafael de Montier P.; Messias,Katharina; Garcia,Denny Marcos; Cardillo,José Augusto; Scott,Ingrid U.; Messias,Andre; Jorge,RodrigoABSTRACT Purpose: To compare visual acuity, macular thickness, and the area of active neovascularization based on fluorescein angiography outcomes associated with standard single-spot panretinal photocoagulation in the Early Treatment Diabetic Retinopathy Study (ETDRS) pattern combined with intravitreal ranibizumab injection versus multiple-spot full scatter (PASCAL) panretinal photocoagulation combined with in...
Quality of bevacizumab (Avastin®) repacked in single-use glass vials for intrav...
Sugimoto,Michelle A. A.; Toledo,Vicente de Paulo Coelho Peixoto de; Cunha,Mariem Rodrigues Ribeiro; Carregal,Virginia M.; Jorge,Rodrigo; Leão,PedroABSTRACT Purpose: Avastin® (bevacizumab) is an anti-vascular endothelial growth factor (VEGF) monoclonal antibody given as an off-label drug by intravitreal administration for treatment of ocular diseases. The drug's clinical application and its cost-benefit profile has generated demand for its division into single-use vials to meet the low volume and low-cost doses necessary for intraocular administration. How...
Structure-functional correlation using adaptive optics, OCT, and microperimetry...
Viana,Karlos Ítalo; Messias,André; Siqueira,Rubens Camargo; Rodrigues,Murilo W.; Jorge,RodrigoABSTRACT We report retinal functional and structural changes of a 40-year-old man diagnosed with occult macular dystrophy. Comprehensive ophthalmological evaluation was performed, followed by spectral-domain optical coherence tomography (SD-OC - Heidelberg) and image acquisition using an adaptive optics (AO) camera (RTX1, Imagine Eyes) for photoreceptor density analysis. Functional tests included full-field ERG...
Multimodal assessment of patients with chronic central serous chorioretinopathy
Viana,Karlos Ítalo Souza; Leão,Pedro M. Souza; Fernandes,Letícia; Siqueira,Rubens; Ribeiro,Jefferson; Jorge,RodrigoABSTRACT Purpose: To examine differences between fluorescein angiography (FA) and indocyanine green angiography (ICG) findings in patients with chronic central serous chorioretinopathy (CSC), comparing these with optical coherence tomography (OCT) findings. Methods: Ten consecutive patients with chronic CSC (19 eyes; 7 men; mean age, 50.7 ± 8.4 years) underwent multimodal evaluation that included FA, ICG, and O...
Photoreceptor assessment using adaptive optics in resolved central serous chori...
Meirelles,André Luiz Braga; Rodrigues,Murilo Wendeborn; Guirado,Aline Fernanda; Jorge,RodrigoABSTRACT We present a case of a patient with resolved central serous chorioretinopathy (CSC) in the left eye with persistent mild visual alterations 4 years after the resolution of the disease. Left eye exam revealed a best corrected visual acuity of 20/25 and a slight change of macular pigmentation. Optical coherence tomography revealed only minor irregularities in the topography of retinal pigment epithelium ...
Choroidal neovascularization silent on optical coherence tomography: report of ...
Borges,Felipe Placeres; Siqueira,Rubens Camargo; Scott,Ingrid Ursula; Cardillo,José Augusto; Jorge,RodrigoABSTRACT Herein, we report two cases of vision loss after successful cataract surgery, associated with drusenoid retinal pigment epithelial detachment without features of choroidal neovascularization on optical coherence tomography along with angiographic examinations suggestive of choroidal neovascularization in which anatomical and functional improvements were achieved with intravitreal injections of anti-vas...
Association of high-density lipoprotein and apolipoprotein E genetic variants w...
Cezario,Sabrina Mayara; Calastri,Maria Clara Jéssica; Oliveira,Camila Ive Ferreira; Carmo,Tayanne Silva; Pinhel,Marcela Augusta de SouzaPurpose: This study aimed to evaluate the association of age-related macular degeneration (AMD) with apolipoprotein E (APOE) variants and serum lipid profiles, including levels and fractions of total serum cholesterol (TC), low-density lipoprotein cholesterol (LDLc), and high-density lipoprotein cholesterol (HDLc), and triglycerides (TG). Methods: Genotyping of APOE-HhaI was performed in 134 patients (study gro...