Encontrados 6 documentos, a visualizar página 1 de 1
Synthesis and Medicinal Applications of N-Heterocyclic Carbene Complexes Based ...
Francescato, Giulia; Leitão, Maria Inês P.S.; Orsini, Giulia; Petronilho, AnaFunding Information: . We kindly acknowledge the support of FCT\u2010 Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia, I.P., through the MOSTMICRO\u2010ITQB R&D Unit (UIDB/04612/2020, UIDP/04612/2020) and LS4FUTURE Associated Laboratory (LA/P/0087/2020) and Fellowships PD/BD/135483/2018 and COVID/BD/152502/2022 (M.I.P.S. Leit\u00E3o), SFRH/BD/144441/2019 (G. Francescato) UI/BD/152076/2021 (G. Orsini). A. ...
Antitumor Activity and Reductive Stress by Platinum(II) N-Heterocyclic Carbenes...
Leitão, Maria Inês P.S.; Turos-Cabal, Maria; Sanchez-Sanchez, Ana Maria; Gomes, Clara S.B.; Herrera, Federico; Martin, Vanesa; Petronilho, AnaFunding Information: We thank Fernanda Murtinheira for the support on the autophagy measurements. This work was supported by FCT – Fundação para a Ciência e a Tecnologia, I.P., through MOSTMICRO‐ITQB R&D Unit (UIDB/04612/2020, UIDP/04612/2020) and LS4FUTURE Associated Laboratory (LA/P/0087/2020). M.I.P.S.L. was supported by fellowships PD/BD/135483/2018 and COVID/BD/152502/2022 from FCT. A.P. acknowledges the c...
Transnational cooperation in enhancing researchers’ wider employability
Lees, James; Gorini, Lucrezia; Torjussen, Stian; Oliveira, Margarida; Pinto, Paula; Potes Barbas, Maria; Martins, Madalena; Jones, Melanie S.Funding Information: Paula Pinto acknowledges the Life Quality Research Centre–UIDP/04748/2020, a programme financially supported by FCT–Fundação para a Ciência e Tecnologia/ Ministério da Educação e Ciência. The project on which this article is based was made possible by an Erasmus+ Strategic Partnership grant from the European Commission (TRANSPEER: a Transnational Project to Enhance the Employability of Rese...
Copper Acts Synergistically With Fluconazole in Candida glabrata by Compromisin...
Gaspar-Cordeiro, Ana; Amaral, Catarina; Pobre, Vânia; Antunes, Wilson; Petronilho, Ana; Paixão, Paulo; Matos, António P.; Pimentel, CatarinaFunding Information: This work was supported by (1) Project LISBOA-01-0145-FEDER-007660 (“Microbiologia Molecular, Estrutural e Celular”) funded by FEDER funds through COMPETE2020 – “Programa Operacional Competitividade e Internacionalização” (POCI); (2) “Fundação para a Ciência e a Tecnologia” (FCT) through programme IF (IF/00124/2015) to CP; (3) the European Union’s Horizon 2020 Research and Innovation Progra...
Synthesis of platinum (II) N-heterocyclic carbenes based on adenosine
Leitão, Maria Inês P. S.; Francescato, Giulia; Gomes, Clara S. B.; Petronilho, AnaFunding Information: This research was funded by national funds through FCT?Funda??o para a Ci?ncia e a Tecnologia, I.P., Project MOSTMICRO-ITQB (refs. UIDB/04612/2020 and UIDP/04612/2020), and IF/00109/2014/CP1244/CT0007. This work was also supported by FCT fellowships number PD/BD/135483/2018 (M.I.P.S.L.) and SFRH/BD/1444412019 (G.F.). Clara S. B. Gomes acknowledges the Associate Laboratory for Green Chemistr...
N-Heterocyclic Carbenes Derived from Guanosine
Leitão, Maria Inês P.S.; Herrera, Federico; Petronilho, AnaPalladium(II) and platinum(II) complexes bearing N-heterocyclic carbenes derived from guanosine are synthesized via oxidative addition, followed by protonation in the presence of acid. Cytotoxicity of the compounds is evaluated in several cell lines. Compounds 2a, 2b, and 3a are selective for glioblastoma U251 cells and are nontoxic toward healthy human embryonic kidney (HEK293) cells.