4 documents found, page 1 of 1
Pediatric Nephrotoxicity: How Aware Are We?
Figueiredo,Cátia Raquel; Durão,Filipa; Zagalo,Ana; Sandes,Ana Rita; Silva,José Eduardo; Stone,RosárioABSTRACT Vancomycin and aminoglycosides are potentially nephrotoxic broad-spectrum antibiotics, which can be used both in the treatment of severe infections and in surgical prophylaxis, in pediatric patients. Prolonged antibiotic therapy and high trough concentrations are associated with toxicity. Additionally, several individual factors contribute to nephrotoxicity increasing the risk of acute kidney injury (A...
Tubulointerstitial nephritis and uveitis syndrome in children: report of three ...
Pereira,Cátia; Gil,Joana; Leal,Inês; Costa-Reis,Patrícia; Silva,José Eduardo Esteves Da; Stone,RosárioABSTRACT Tubulointerstitial nephritis and uveitis syndrome is a rare and probably underdiagnosed condition. Renal and ocular manifestations may not occur simultaneously, making the diagnosis more difficult. Nephritis may be asymptomatic; therefore, renal function evaluation is essential for diagnosis. Urinary β2-microglobulin levels may be particularly useful. Uveitis, mostly anterior, nongranulomatous and bila...
Pediatric pulmonary embolism and nephrotic syndrome
Costa,Raquel; Gomes,Susana; Stone,Rosário; Ferreira,RosárioThromboembolic complications, such as pulmonary embolism, are well-documented complications in nephrotic syndrome. The authors report a case of a 10-year-old boy with nephrotic syndrome and history of thrombotic complications, who experienced a massive pulmonary embolism during nephrotic syndrome relapse. Clinical signs and symptoms were minimal; D-dimers were an important clue and computed tomography pulmonary...
Growing up with chronic renal disease - The road remains rocky
Rodrigues,Natacha; Pereira,Marta; Neves,Fernando; Jorge,Sofia; Almeida,Margarida; Stone,Rosário; da Costa,GomesBackground: Understanding the aetiology and approach to management of chronic kidney disease presenting in the paediatric age range continues to represent a true challenge. With the improvement of paediatric care, the number of patients reaching adulthood has increased in recent decades, and it is well known that the transition period from paediatric to adult care is critical; it is associated with a high rate ...