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Zebrafish xenografts as a fast screening platform for bevacizumab cancer therapy

Almeida, C; Mendes, R; Pezzarossa, A; Gago, J; Carvalho, C; Alves, A, et al.

Cancer is the second leading cause of death in the world. Given that cancer is a highly individualized disease, predicting the best chemotherapeutic treatment for individual patients can be difficult. Ex vivo models such as mouse patient-derived xenografts (PDX) and organoids are being developed to predict patient-specific chemosensitivity profiles before treatment in the clinic. Although promising, these model...


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