7 documents found, page 1 of 1
Presence of starch enhances in vitro biodegradation and biocompatibility of a g...
Balmayor, E. R.; Baran, T. E.; Unger, M.; Marques, A. P.; Azevedo, H. S.; Reis, R. L.The effect of α-amylase degradation on the release of gentamicin from starch-conjugated chitosan microparticles was investigated up to 60 days. Scanning electron microscopic observations showed an increase in the porosity and surface roughness of the microparticles as well as reduced diameters. This was confirmed by 67% weight loss of the microparticles in the presence of α-amylase. Over time, a highly porous m...
Identification of Osteoarthritic cell receptors by phage display for cartilage ...
Martins, Ivone M.; Pereira, Ricardo Nuno Correia; Nóbrega, Franklin L.; Kluskens, Leon; Azeredo, Joana; Reis, R. L.; Azevedo, H. S.info:eu-repo/semantics/publishedVersion
Phage display technology - Potential and Applications
Martins, Ivone M.; Nóbrega, Franklin L.; Ferreira, Débora; Silva, A.; Azevedo, H. S.; Reis, R. L.; Kessels, Helmut; Rodrigues, L. R.; Azeredo, Joana2nd Hands-on Phage Biotechnology Course; info:eu-repo/semantics/publishedVersion
Peptide ligands identified by phage display technology to develop a targeted na...
Martins, Ivone M.; Pereira, Ricardo Nuno Correia; Kluskens, Leon; Azeredo, Joana; Reis, R. L.; Azevedo, H. S.info:eu-repo/semantics/publishedVersion
Novel biodegradable polymeric microparticles for the localized delivery of diff...
Balmayor, Elizabeth Rosado; Bessa, P. C.; Tuzlakoglu, Kadriye; Azevedo, H. S.; Casal, Margarida; Reis, R. L.[Excerpt] Growth and differentiation factors can be used to guide the biology in tissue engineering, ranging from promoting cell proliferation, to morphogenic activities initiating a cascade of events leading to tissue formation in vivo. Synthetic glucocorticoids (e.g. dexamethasone, DEX) and bone morphogenetic proteins (BMPs) are particularly relevant in bone tissue engineering, as they are able to induce oste...
Starch/ethylene-co-vinyl alcohol fiber mesh scaffolds: Production, characteriza...
Pashkuleva, I.; Azevedo, H. S.; López-Pérez, P. M.; Reis, R. L.[Excerpt] Tissue engineering scaffolds must provide cell anchorage sites, mechanical stability and structural guidance. Fiber mesh structures have been considered as adequate scaffolds for tissue engineering due their high surface area available for the adhesion and proliferation of different cell types. In addition, they present a good degree of interconnectivity between pores, which is essential for the migra...
Novel injectable gel encapsulating human articular chondrocytes for cartilage t...
Pereira, R. C.; Scaranari, M.; Azevedo, H. S.; Reis, R. L.; Cancedda, R.; Gentili, C.[Excerpt] Cartilage tissue loss, as a result of trauma, congenital disorders and diseases of joints, involving structural damage of articular cartilage surface, is a substantial clinical problem representing a major challenge for cartilage tissue engineering. The aim of our study was to evaluate the in vitro and in vivo behavior of human articular chondrocytes encapsulated within a novel carrageenan in situ inj...