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Influence of puncture devices on the accuracy of cyclophosphamide dosing for ch...

Carvalho, Susana; Cardoso, Andreia; Ferreira, Débora; Silva, Diana Dias da; Moreira, Fernando; Moreira, Fernando; Dias da Silva, Diana Cristina

Cyclophosphamide is one of the most commonly used cytotoxic drugs in chemotherapy protocols. Its preparation in the hospital setting involves handling concentrated solutions, which pose occupational exposure risks and potential variations in the final dose administered. The aim of this study was to evaluate the effect of aspiration devices on the concentration of cyclophosphamide in reconstituted solutions. An ...


Safeguarding patients, relatives, and nurses: A screening approach for detectin...

Cardoso, Andreia; Jesus, Ângelo; Barreiros, Luísa; Carvalho, Daniel; Sá, Maria dos Anjos; Carvalho, Susana; Correia, Patrícia; Moreira, Fernando

The leakage of 5-fluorouracil (5-FU) from elastomeric infusion pumps used in cancer therapy poses a potential risk of unintentional exposure to multiple individuals, including patients’ relatives and healthcare professionals, and may also compromise the accurate administration of 5-FU dosages to patients. This study aimed to develop, validate, and apply an analytical method to detect and quantify 5-FU residues ...


Predictors of baboon sleep site selection in gorongosa national park

Lewis‐Bevan, Lynn; Hammond, Philippa; Carvalho, Susana; Biro, Dora

Objectives: This research aimed to understand how sleep site selection compared to other study sites in baboons living in a lowpredator density, highly seasonal environment. We compared baboon troops in two distinct habitat types with different seasonal influences within the park, one that flooded annually and one that did not. We compared their sleep site use, reuse, and location relative to home range boundar...


Engineering skills in the manufacture of tools by wild chimpanzees

Pascual-Garrido, Alejandra; Carvalho, Susana; Mjungu, Deus; Schulz-Kornas, Ellen; Casteren, Adam van

Physical evidence of early hominin perishable tools is scarce. However, it is reasonable to assume the mechanical constraints surrounding tool use and manufacture have remained somewhat constant. Using a functional framework to understand the technical capabilities of extant hominoid tool users presents a novel approach to predict the perishable tool-using capabilities of our earliest relatives. We investigated...


Self-directed and prosocial wound care, snare removal, and hygiene behaviors am...

Freymann, Elodie; Hobaiter, Catherine; Huffman, Michael Alan; Klein, Harmonie; Muhumuza, Geresomu; Reynolds, Vernon; Slania, Nora E.; Soldati, Adrian

Understanding the cognitive and social foundations of healthcare behaviors in humans requires examining their evolutionary precursors in our closest living relatives. Investigating self-directed and other-directed healthcare in chimpanzees provides crucial insights into the origins of medicinal knowledge, identification of specific medicinal resources used for health maintenance, and the emergence of prosocial ...


Evolution of craniofacial shape in relation to sexual dimorphism in theropithec...

Ossorio, Ángeles; Figueroa-Torrejón, Ambra; Buston, Rodrigo; Caldon, Matteo; Mathe, Jacinto; Doria, Giuliano; Gippoliti, Spartaco; Volta, Antonella

Introduction: Sexual dimorphism in cranial morphology is a significant aspect of primate evolution, providing insights into evolutionary pressures and mating systems in different species. This study focuses on cranial sexual dimorphism in Papio and Theropithecus, two closely related genera within the tribe Papionini.Methods: Using geometric morphometric techniques, we analyzed 570 cranial specimens from both ge...


Sex-mediated gene flow in grayfoot chacma baboons (Papio ursinus griseipes) in ...

Silva, Maria Joana Ferreira da; Tralma, Paula; Colmonero-Costeira, Ivo; Cravo-Mota, Mariana; Farassi, Rassina; Hammond, Philippa; Lewis-Bevan, Lynn

Dispersal behavior influences gene flow and the spatial distribution of genetic diversity, which is crucial for a species' evolutionary trajectory and population persistence under environmental changes. We used gene flow as a proxy to investigate dispersal patterns in the grayfoot chacma baboon (Papio ursinus griseipes) in Gorongosa National Park (GNP), central Mozambique. The baboons inhabit a mosaic landscape...


West Side Story: regional inter‐troop variation in baboon bark‐stripping at gor...

Biro, Dora; Muschinski, Jana; Hammond, Philippa; Bobe, René; Bamford, Marion K.; Capelli, Cristian; de Oliveira Coelho, João; Farassi, Rassina

Objectives: Baboons possess sophisticated physical and social cognitive abilities; hence, the lack of evidence to date of large-scale behavioral variation in these primates is puzzling. Here we studied a candidate for such variation—the stripping of barkfrom Acacia robusta trees for consumption of the sap and soft tissue underneath—in Gorongosa National Park, Mozambique.Materials and Methods: We surveyed an are...


West side story: regional inter‐troop variation in baboon bark‐stripping at gor...

Biro, Dora; Muschinski, Jana; Hammond, Philippa; Bobe, René; Bamford, Marion K.; Capelli, Cristian; de Oliveira Coelho, João; Farassi, Rassina

Objectives: Baboons possess sophisticated physical and social cognitive abilities; hence, the lack of evidence to date of largescale behavioral variation in these primates is puzzling. Here we studied a candidate for such variation—the stripping of bark from Acacia robusta trees for consumption of the sap and soft tissue underneath—in Gorongosa National Park, Mozambique. Materials and Methods: We surveyed an ar...


Stone selection by wild chimpanzees shares patterns with Oldowan hominins

Braun, D. R.; Carvalho, Susana; Kaplan, R. S.; Beardmore-Herd, Megan; Plummer, T.; Biro, D.; Matsuzawa, T.

The use of broad tool repertoires to increase dietary flexibility through extractive foraging behaviors is shared by humans and their closest living relatives (chimpanzees, Pan troglodytes). However, comparisons between tool use in ancient human ancestors (hominins) and chimpanzees are limited by differences in their toolkits. One feature shared by primate and hominin toolkits is rock selection based on physica...


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