11 documents found, page 1 of 2

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EPICE cohort: two-year neurodevelopmental outcomes after very preterm birth

Draper, ES; Zeitlin, J; Manktelow, BN; Piedvache, A; Cuttini, M; Edstedt Bonamy, AK; Maier, R; Koopman-Esseboom, C; Gadzinowski, J; Boerch, K

Objective: To determine whether the variation in neurodevelopmental disability rates between populations persists after adjustment for demographic, maternal and infant characteristics for an international very preterm (VPT) birth cohort using a standardised approach to neurodevelopmental assessment at 2 years of age. Design: Prospective standardised cohort study. Setting: 15 regions in 10 European countries. Pa...


Mode of delivery and mortality and morbidity for very preterm singleton infants...

Schmidt, S; Norman, M; Misselwitz, B; Piedvache, A; Huusom, LD; Varendi, H; Barros, H; Cammu, H; Blondel, B; Dudenhausen, J; Zeitlin, J; Weber, T

Objective Caesarean section (CS) may reduce mortality and morbidity for very preterm breech infants, but evidence is inconclusive. We evaluated neonatal outcomes for singleton breech infants by mode of delivery in a European cohort. Study design Data come from the EPICE population-based cohort of very preterm births in 19 regions in 11 European countries (7770 live births). The study population was singleton sp...


Low breastfeeding continuation to 6 months for very preterm infants: A European...

Bonnet, C; Blondel, B; Piedvache, A; Wilson, E; Bonamy, AE; Gortner, L; Rodrigues, C; van Heijst, A; Draper, ES; Cuttini, M; Zeitlin, J

Breastfeeding confers multiple benefits for the health and development of very preterm infants, but there is scarce information on the duration of breastfeeding after discharge from the neonatal intensive care unit (NICU). We used data from the Effective Perinatal Intensive Care in Europe population‐based cohort of births below 32 weeks of gestation in 11 European countries in 2011–2012 to investigate breastfee...


Duration and Time Trends in Hospital Stay for Very Preterm Infants Differ Acros...

Maier, RF; Blondel, B; Piedvache, A; Misselwitz, B; Petrou, S; Van Reempts, P; Franco, F; Barros, H; Gadzinowski, J; Boerch, K; van Heijst, A

Objectives: To compare duration and changes over time in length of hospital stay for very preterm and extremely preterm infants in 10 European regions. Design: Two area-based cohort studies from the same regions in 2003 and 2011/2012. Setting: Ten regions from nine European countries. Patients: Infants born between 22 + 0 and 31 + 6 weeks of gestational age and surviving to discharge (Models of Organising Acces...


Cohort study from 11 European countries highlighted differences in the use and ...

Wilson, E; Zeitlin, J; Piedvache, A; Misselwitz, B; Christensson, K; Maier, RF; Norman, M; Edstedt Bonamy, AK; Barros, H; Rodrigues, C; Rodrigues, T

AIM: This study investigated the different strategies used in 11 European countries to prevent hypothermia, which continues to affect a large proportion of preterm births in the region. METHODS: We examined the association between the reported use of hypothermia prevention strategies in delivery rooms and body temperatures on admission to neonatal intensive care units (NICUs) in 5861 infants born at 22 + 0 to 3...


Wide variation in severe neonatal morbidity among very preterm infants in Europ...

Bonamy, AK; Zeitlin, J; Piedvache, A; Maier, RF; van Heijst, A; Varendi H; Manktelow BN; Fenton A; Mazela J; Cuttini M; Norman M; Petrou S; Reempts PV

Objective To investigate the variation in severe neonatal morbidity among very preterm (VPT) infants across European regions and whether morbidity rates are higher in regions with low compared with high mortality rates. Design Area-based cohort study of all births before 32 weeks of gestational age. Setting 16 regions in 11 European countries in 2011/2012. Patients Survivors to discharge from neonatal care (n=6...


Variation in term birth weight across European countries affects the prevalence...

Zeitlin, J; Bonamy, AK; Piedvache, A; Cuttini, M; Barros, H; Van Reempts, P; Mazela, J; Jarreau, PH; Gortner, L; Draper, ES; Maier, RF

Aim: This study assessed the prevalence of small for gestational age (SGA) among very preterm (VPT) infants using national and European intrauterine references. Methods. We generated country‐specific and common European intrauterine growth references for 11 European countries, according to Gardosi's approach and Hadlock's foetal growth model, using national data on birthweights by sex. These references were app...


Association of Short Antenatal Corticosteroid Administration-to-Birth Intervals...

Norman, M; Piedvache, A; Børch, K; Huusom, LD; Bonamy, AK; Howell, EA; Jarreau, PH; Maier, RF; Pryds, O; Toome, L; Varendi, H; Weber, T; Wilson, E

Administration-to-birth intervals of antenatal corticosteroids (ANS) vary. The significance of this variation is unclear. Specifically, to our knowledge, the shortest effective administration-to-birth interval is unknown. Objective:To explore the associations between ANS administration-to-birth interval and survival and morbidity among very preterm infants. Design, Setting, and Participants: The Effective Perin...


Changes in management policies for extremely preterm births and neonatal outcom...

Bonet, M; Cuttini, M; Piedvache, A; Boyle, EM; Jarreau, PH; Kollée, L; Maier, RF; Milligan, DW; van Reempts, P; Weber, T; Barros, H; Gadzinowki, J

Objective: To investigate changes in maternity and neonatal unit policies towards extremely preterm infants (EPTIs) between 2003 and 2012, and concurrent trends in their mortality and morbidity in ten European regions. Design: Population-based cohort studies in 2003 (MOSAIC study) and 2011/2012 (EPICE study) and questionnaires from hospitals. Setting: 70 hospitals in ten European regions. Population: Infants bo...


Use of evidence based practices to improve survival without severe morbidity fo...

Zeitlin, J; Manktelow, BN; Piedvache, A; Cuttini, M; Boyle, E; van Heijst, A; Gadzinowski, J; van Reempts, P; Huusom, L; Weber, T; Schmidt, S; Barros, H

Objectives To evaluate the implementation of four high evidence practices for the care of very preterm infants to assess their use and impact in routine clinical practice and whether they constitute a driver for reducing mortality and neonatal morbidity. Design Prospective multinational population based observational study. Setting 19 regions from 11 European countries covering 850 000 annual births participati...


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