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Hazard identification and characterization of leachable chemicals from plastic ...

Dirven, Hubert; Bogusz, Aleksandra; Hans Bouwmeester; Busch, Mathias; Duflos, Guillaume; Eriksen, Gunnar S.; Fardilha, Margarida; Flores-Gomez, Daniela

A recent study has suggested that plastics may contain more than 16,000 chemicals, including additives, processing aids, starting substances, intermediates and Non-Intentionally Added Substances. Plastic chemicals are released throughout the plastic life cycle, from production, use, disposal and recycling. Most of these chemicals have not been studied for potential hazardous properties for humans and in the env...


Application of the adverse outcome pathway (AOP) concept to structure the avail...

van Bilsen, Jolanda H. M.; Sienkiewicz‑Szłapka, Edyta; Lozano‑Ojalvo, Daniel; Willemsen, Linette E. M.; Antunes, Célia M.; Molina, Helena

Background: The introduction of whole new foods in a population may lead to sensitization and food allergy. This constitutes a potential public health problem and a challenge to risk assessors and managers as the existing understanding of the pathophysiological processes and the currently available biological tools for prediction of the risk for food allergy development and the severity of the reaction are not ...


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