13 documents found, page 1 of 2
Generation and validation of a classification model to diagnose familial hyperc...
Albuquerque, João; Medeiros, Ana Margarida; Alves, Ana Catarina; Jannes, Cinthia Elim; Mancina, Rosellina M.; Pavanello, Chiara; Chora, Joana RitaBackground and aims: The early diagnosis of familial hypercholesterolaemia is associated with a significant reduction in cardiovascular disease (CVD) risk. While the recent use of statistical and machine learning algorithms has shown promising results in comparison with traditional clinical criteria, when applied to screening of potential FH cases in large cohorts, most studies in this field are developed using...
Genomic insight into the origins and dispersal of the Brazilian coastal natives
Pereira, Alexandre da Costa
Heritability and sex-specific genetic efects of self-reported physical activity...
Pereira, Alexandre da Costa
Integrated proteomics and metabolomics analysis reveals differential lipid meta...
Pereira, Alexandre da Costa
Prevalência de Doença Arterial Periférica e Fatores de Risco Associados em uma ...
Pereira, Alexandre da Costa
Cohort profile: the Baependi Heart Study : a family-based, highly admixed cohor...
Pereira, Alexandre da Costa
Projeto corações do Brasil.
Nascimento Neto, Raimundo Marques do; Krieger, José Eduardo; Coelho, George Luiz Lins Machado; Pereira, Alexandre da Costa
BDKRB2 +9/−9 polymorphism Is associated with higher risk for diabetes mellitus ...
Alvim, Rafael de Oliveira; Santos, Paulo Caleb Júnior de Lima; Nascimento Neto, Raimundo Marques do; Coelho, George Luiz Lins MachadoSome mechanisms have been proposed to explain the role of bradykinin on glucose homeostasis and some studies reported that the BDKRB2 +9/−9 polymorphism was associated to the transcriptional activity of the receptor. In this scenario, the main aim of this study was to evaluate the association of the BDKRB2 +9/−9 polymorphism with diabetes mellitus risk in the Brazilian general population. This study included 1,...
Self-declared ethnicity associated with risk factors of cardiovascular diseases...
Santos, H. C.; Fragoso, T. M.; Coelho, George Luiz Lins Machado; Nascimento Neto, Raimundo Marques do; Mill, José Geraldo; Krieger, José Eduardo
SLCO1B1 RS4149056 polymorphism associated with statin-induced myopathy is diffe...
Santos, Paulo Caleb Júnior de Lima; Soares, Renata A. G.; Nascimento Neto, Raimundo Marques do; Coelho, George Luiz Lins Machado; Mill, José GeraldoBackground: Recent studies reported the association between SLCO1B1 polymorphisms and the development of statin-induced myopathy. In the scenario of the Brazilian population, being one of the most heterogeneous in the world, the main aim here was to evaluate SLCO1B1 polymorphisms according to ethnic groups as an initial step for future pharmacogenetic studies. Methods: One hundred and eighty-two Amerindians plu...