2 documents found, page 1 of 1
The Role of Multidimensional Prognostic Index to Identify Hospitalized Older Ad...
Custodero, C; Veronese, N; Topinkova, E; Michalkova, H; Polidori, MC; Cella, A; Cruz-Jentoft, AJ; von Arnim, CAF; Azzini, M; Gruner, H; Castagna, ABackground: Data regarding the importance of multidimensional frailty to guide clinical decision making for remdesivir use in older patients with coronavirus disease 2019 (COVID-19) are largely unexplored. Objective: The aim of this research was to evaluate if the Multidimensional Prognostic Index (MPI), a multidimensional frailty tool based on the Comprehensive Geriatric Assessment (CGA), may help physicians i...
Current Evidence on the Impact of Medication Optimization or Pharmacological In...
Pazan, F; Petrovic, M; Cherubini, A; Onder, G; Cruz-Jentoft, A; Denkinger, M; van der Cammen, T; Stevenson, J; Ibrahim, K; Rajkumar, C; Bakken, MBackground: Frailty and adverse drug effects are linked in the fact that polypharmacy is correlated with the severity of frailty; however, a causal relation has not been proven in older people with clinically manifest frailty. Methods: A literature search was performed in Medline to detect prospective randomized controlled trials (RCTs) testing the effects of pharmacological interventions or medication optimiza...