13 documents found, page 1 of 2
Label-free optical biopsy of colorectal phantoms using a custom-made multi-phot...
Freitas, R. B.; Rodrigues, M. J. L. F.; Cunha, N. F.; Pimenta, S.; Belsley, M.; Correia, J. H.; Maciel, M. J.Colorectal cancer is a global health concern, emphasizing the need for early detection tools (Xi and Xu, 2021). Endogenous fluorophores such as nicotinamide adenine dinucleotide (phosphate) (NAD(P)H) and flavin adenine dinucleotide (FAD) play essential roles in cellular metabolism. Their fluorescence signals can reveal metabolic changes in tumoral tissues (Lakowicz, 2006; Benninger and Piston, 2013; Cao, Wallra...
How socially responsible human resource management fosters work engagement: The...
Pimenta, S.; Duarte, A.P.; Simões, E.Purpose – In recent years, efforts to reinforce the links between corporate social responsibility and human resource management have highlighted employees’ role as crucial organizational stakeholders. This study aims to investigate whether workers’ perception of socially responsible human resource management (SR-HRM) based on employee-focused practices is related to work engagement (WE). This research also expl...
Immune-mediated skin lesions related to biological disease-modifying antirheuma...
Martins, A.; Oliveira, D. Santos; Martins, F. R.; Nicolau, R.; Pinheiro, F. Oliveira; Rato, M.; Bernardo, A.; Pimenta, S.; Bernardes, M.; Costa, L.Biological disease-modifying antirheumatic drugs (bDMARDs) have revolutionized the treatment of chronic inflammatory rheumatic diseases. However, the physician and the patient should be aware of possible adverse reactions. Skin is one of the most frequent organs involved in bDMARD adverse reactions and immune-mediated skin lesions (IMSL) have rarely been described before in cohort studies and their incidence is...
Adalimumab and number of previous biological disease-modifying antirheumatic dr...
Martins, A.; Oliveira, D. Santos; Martins, F. R.; Nicolau, R.; Pinheiro, F. Oliveira; Rato, M.; Bernardo, A.; Pimenta, S.; Bernardes, M.; Costa, L.Treatment of inflammatory rheumatic diseases has dramatically changed with the introduction of biologic disease modifying anti-rheumatic drugs (bDMARDs). However, these drugs aren’t exempt from risks and skin lesions are the most frequent adverse reactions. Among the possible adverse skin reactions, immune-mediated skin lesions (IMSL) may occur. Risk factors associated with the occurrence of IMSL in rheumatic p...
Detailed experimental validation and benchmarking of six models for longitudina...
Breite, C.; Melnikov, A.; Turon, A.; de Morais, A. B.; Le Bourlot, C.; Maire, E.; Schöberl, E.; Otero, F.; Mesquita, F.; Sinclair, I.; Costa, J.Longitudinal tensile failure of unidirectional fibre-reinforced composites remains difficult to predict accurately. The key underlying mechanism is the tensile failure of individual fibres. This paper objectively measured the relevant input data and performed a detailed experimental validation of blind predictions of six state-of-the-art models using high-resolution in-situ synchrotron radiation computed tomogr...
Are indoor and outdoor opportunities for physical activity related to active be...
Hipólino, N.; Flora, S.; Gordo, J.; Pimenta, S.; Morais, N.; Silva, C. G.; Ribeiro, J.; Silva, F.; Oliveira, A.; Brites-Pereira, M.; Carreira, B. P.Introduction: Persistent respiratory symptoms at rest and during exertion (e.g., dyspnea, fatigue) play a role on the low physical activity (PA) levels found in people with chronic obstructive pulmonary disease (COPD), but other factors may also be involved. Environmental factors have been shown to impact PA levels in other patient populations, but evidence regarding people with COPD is still scarce. Investigat...
Blind benchmarking of seven longitudinal tensile failure models for two virtual...
Breite, C.; Melnikov, A.; Turon, A.; Morais, A.B. de; Otero, F.; Mesquita, F.; Costa, J.; Mayugo, J.A.; Guerrero, J.M.; Gorbatikh, L.; McCartney, L.N.Many models for prediction of longitudinal tensile failure of unidirectional (UD) composites have been developed in the last decades. These models require significant assumptions and simplifications, but their consequences for the predictions are often not clearly understood. This paper therefore presents a blind benchmark of seven different models applied to two virtual materials. Reliably capturing the locali...
Design of a novel TiO2/airgap-based polarizing micro beam splitter cube
Maciel, M. J.; Pimenta, S.; Ribeiro, J. F.; Correia, J. H.Polarizing beam splitters are key elements widely used in different optical instruments. This paper introduces the design and simulation of a novel thin-film multilayer polarizing micro beam splitter based on airgap layers (n = 1.002828 at 400 nm). The negligible absorption coefficient of the air over a wide spectral region (κ ≈ 0 from about 200 nm and higher) satisfies the conditions of a perfect low refractiv...
Portuguese Recommendations for the use of biological therapies in patients with...
Duarte, C.; Sousa-Neves, J.; Águeda, A.; Ribeiro, P.; Daniel, A.; Eugénio, G.; Serra, S.; Araújo, F.; Barcelos, A.; Filipe, B.; Bernardes, M.
Portuguese recommendations for the use of biological therapies in patients with...
Machado, P. M.; Cerqueira, M.; Ávila-Ribeiro, P.; Aguiar, R.; Bernardo, A.; Sepriano, A.; Águeda, A.; Cordeiro, A.; Raposo, A.; Rodrigues, A. M.