13 documents found, page 1 of 2

Pâncreas Anular: Diagnóstico no Adulto

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Gaucher disease and Lupus: a rare association?

Gaucher disease (GD), is an autosomal recessive lysosomal storage disease that is due to mutations in the glucocerebrosidase (GC) gene, with a prevalence of 1/57,000 to 1/75,000 births worldwide and significantly more common among the Ashkenazi Jewish heritage. GD is categorized into three clinical types4 and the clinical manifestations result from the accumulation of the lipid-laden macrophages in the spleen, ...

Calcific uraemic arteriolopathy - A mini-review

Calcific Uraemic Arteriolopathy (CUA) or calciphylaxis, is a thrombotic disorder of skin and subcutaneous tissue which typically presents with painful purpuric nodules that may progress to necrotic ulcers, and is a severe, life-threatening condition. CUA is an uncommon clinical entity that affects mostly haemodialysis (HD) patients. Although the process of vascular calcification was initially thought to be the ...

Risk factors of hip fractures in chronic kidney disease patients

In the Western World the general population is getting older. This implies a higher prevalence of osteoporosis as well as a greater incidence of patients with chronic kidney disease. These two conditions increase the riskof bone fractures. Metabolic and hormonal disarrangement in end-stage renal disease (ESRD) negativelyaffects bone remodeling as it promotes a decrease in Vitamin D availability, hyperphosphatem...

Altered serum levels of FGF-23 and magnesium are independent risk factors for a...

Aims: To investigate the role of FGF-23 and magnesium in relation to the albumin-to-creatinine ratio in type 2 diabetics with chronic kidney disease (CKD) stages 2-4.Methods: In a cross-sectional study we included all eligible type 2 diabetic patients with CKD stages 2-4, followed in our outpatient Diabetic Kidney clinic. We used descriptive statistics, the Student's t-test, ANOVA and the chi-square tests. Our ...

Mineral metabolism and inflammation: factors related to left ventricular hypert...

Left ventricular hypertrophy (LVH) is an important risk factor for cardiovascular disease in patients with diabetic nephropathy (DN) and is an independent predictor of mortality in patients with chronic kidney disease (CKD). The aim of this study was to evaluate the association of LVH with mineral metabolism and inflammation in a population of patients with DN. In an observational study were included 119 type 2...

Fracturing issue concerning cardiovascular mortality in chronic kidney disease ...

With the ageing of population worldwide, the riskof both osteoporosis and chronic kidney disease increased. These two conditions multiply the riskof bone fractures. The higher riskoffractures in CKD is accompanied bya higher mortality rate in hemodialysis patients. According to the Universityof Michigan’s study,the risk mortalityafter hip fracturewas 6.5 times higher in stage 5 CKD patients compared with patien...

Chitin-glucan complex production by Komagataella pastoris: Downstream optimizat...

Purified chitin-glucan complex (CGC(pure)) was extracted from Komagataella pastoris biomass using a hot alkaline treatment, followed by neutralization and repeated washing with deionized water. The copolymer thus obtained had a beta-glucan:chitin molar ratio of 75:25 and low protein and inorganic salts contents (3.0 and 0.9 wt%, respectively). CGC(pure) had an average molecular weight of 4.9 x 10(5) Da with a p...

Marcadores conversacionais e ensino-aprendizagem do português como língua estra...

Marcadores conversacionais em Português Língua Estrangeira : da teoria à prática

This study aims to present an appropriate sample of activities focused on Conversational process of Portuguese as a Foreign Language (PFL). By taking into account learners’ specific needs in the oral domain, i.e., a lack or incipient use of CM– a research project was implemented regarding a global development of their oral skills (comprehension and production), and especially centred in a more consistent and ad...