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Evaluation of criteria of manual blood smear review following automated complet...

Comar,Samuel Ricardo; Malvezzi,Mariester; Pasquini,Ricardo

Abstract Background: There is great interest in reducing the number of automated complete blood counts requiring manual blood smear reviews without sacrificing the quality of patient care. This study was aimed at evaluating and establishing appropriate screening criteria for manual blood smear reviews to improve the performance in a hematology laboratory. Method: A total of 1977 consecutive samples from the dai...

Data: 2017   |   Origem: Oasisbr

Proposal for the standardization of flow cytometry protocols to detect minimal r...

Ikoma,Maura Rosane Valério; Beltrame,Miriam Perlingeiro; Ferreira,Silvia Inês Alejandra Cordoba Pires; Souto,Elizabeth Xisto; Malvezzi,Mariester

ABSTRACT Minimal residual disease is the most powerful predictor of outcome in acute leukemia and is useful in therapeutic stratification for acute lymphoblastic leukemia protocols. Nowadays, the most reliable methods for studying minimal residual disease in acute lymphoblastic leukemia are multiparametric flow cytometry and polymerase chain reaction. Both provide similar results at a minimal residual disease lev...

Data: 2015   |   Origem: Oasisbr

Paroxysmal nocturnal hemoglobinuria clone in 103 Brazilian patients: diagnosis ...

Azambuja,Ana Paula de; Malvezzi,Mariester; Bitencourt,Marco Antonio; Oliveira,Michel Michels; Medeiros,Larissa Alessandra; Pasquini,Ricardo

Background: Paroxysmal nocturnal hemoglobinuria is an acquired chronic hemolytic ane- mia, which often manifests as peripheral blood cytopenias and thrombosis. Objective: The aim of this study is to describe a Brazilian population of paroxysmal nocturnal hemoglobinuria patients. Methods: One hundred and three paroxysmal nocturnal hemoglobinuria cases were retrospectively reviewed and the clinical presentation, ...

Data: 2015   |   Origem: Oasisbr

Are the review criteria for automated complete blood counts of the Internationa...

Comar,Samuel Ricardo; Malvezzi,Mariester; Pasquini,Ricardo

OBJECTIVE: to verify whether the review criteria for automated blood counts suggested by the International Consensus Group for Hematology Review of the International Society for Laboratory Hematology are suitable for the Hematology Laboratory of Hospital de Clinicas, Universidade Federal do Paraná.METHODS: initially, the review criteria of the International Society for Laboratory Hematology were adapted due to ...

Data: 2014   |   Origem: Oasisbr

Análise imunofenotípica de subpopulações linfocitárias do sangue periférico na ...

Ercole,Linete Parolin; Malvezzi,Mariester; Boaretti,Antonio Carlos; Utiyama,Shirley Ramos da Rosa; Rachid,Acir; Radominski,Sebastião Cezar

A esclerose sistêmica (ES) é uma doença inflamatória crônica do tecido conjuntivo, de etiologia desconhecida, caracterizada por fibrose e dano micro vascular dos órgãos afetados. Há várias evidências de que a ativação do sistema imune celular participa de maneira expressiva na sua patogênese. OBJETIVO: Analisar numericamente as subpopulações linfocitárias no sangue periférico de pacientes com ES e sua possível ...

Data: 2003   |   Origem: Oasisbr

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