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Practical Guidance on the Detection of NTRK Fusions in Sarcomas

Fernandes, Isabel; Macedo, Daniela; Gouveia, Emanuel; Ferreira, Ana; Lima, Jorge; Lopez, Dolores; Melo-Alvim, Cecília; Carvalho, Alice; Tavares, Paulo

Publisher Copyright: © 2025 CELOM. All rights reserved.; Sarcomas are a rare and heterogeneous group of mesenchymal malignant tumors and account for approximately 1% of all adult cancers and around 20% of all pediatric solid tumors in Europe. Technology advances have enabled a more accurate and efficient characterization of the molecular mechanisms underlying the pathogenesis of sarcoma subtypes and revealed no...


Subtherapeutic Dose of Ionizing Radiation Reprograms the Pre-Metastatic Lung Ni...

Oliveira, Paula de; Vala, Inês Sofia; Faísca, Pedro; Guimaraes, Joao C.; Pina, Filomena; Poli, Esmeralda; Diegues, Isabel; Osório, Hugo

Funding Information: We thank the Radiotherapy Service, ULSSM, Lisbon, Portugal, particularly C. Raimundo, P. Aresta, P. Ribeiro, A. Maduro, J. Pereira, M. Pereira, A. Castro, C. Isidoro, and R. Pinto for their help in irradiation delivery, and R. Ferreira for treatment planning and dosimetry. I.S.V. holds a research position funded by FCT under the program contract CEEC-INST/00106/2021. J.C.G. is supported by ...


Molecular Changes In Cardiac Tissue As A New Marker To Predict Cardiac Dysfunct...

Ribeiro, Sónia; Simões, Ana Rita; Rocha, Filipe; Vala, Inês Sofia; Pinto, Ana Teresa; Ministro, Augusto; Poli, Esmeralda; Diegues, Isabel Maria

Funding Information: This work was supported by the European Community’s Horizon 2020 Program supported the MEDIRAD—Implications of Medical Low Dose Radiation Exposure granted by the Euratom Research and Training Program 2014-2014 under agreement No. 755523. The MS work was financed by the Portuguese Mass Spectrometry Network, integrated in the National Roadmap of Research Infrastructures of Strategic Relevance...


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