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Synthesis, photophysical and spectroscopic characterization of amphiphilic D-A-...

Boland, Mathilde; Pinto, Sónia; Gomes-da-Silva, Lígia C.; Pina, João; Costa, Susana P. G.; Raposo, M. Manuela M.

Two positively charged amphiphilic benzothiadiazole derivatives with a Donor-Acceptor-π spacer-Acceptor structure (D-A-π-A) were developed, based on a methoxy-phenyl-benzothiadiazole model compound, by adopting methoxy-phenyl as the electron donor and 2,1,3-benzothiadiazole and 2,3-dimethylbenzothiazol-3-ium or 2,3-dimethylnaphtothiazol-3-ium iodide as combined electron acceptors. The aim of the study was to in...


A comprehensive exploration of optical properties of GdAlO3: Cr3+

Souissi, Hajer; Kammoun, S.; Dhahri, E.; Pina, João; Costa, Benilde F. O.; Fausto, Rui

This study focused on the optical properties of the Cr3+-doped GdAlO3 perovskite,through comprehensive analysis of its photoluminescence spectra. The GdAlO3:Cr3+perovskite,synthesized by a traditional solid-state process, crystallizes in theorthorhombicPbnmspacegroup, with Cr3+ions substituting Al3+ ions in octahedral sites. Photoluminescence excitation and emission spectra of the material were obtained and ass...


Robot-Assisted Radical Cystectomy with Orthotopic Studer Neobladder and Preserv...

Medeiros, Mariana; Andrade, Vanessa; Gomes, Aléxia; Ferronha, Frederico; Pina, João; Campos Pinheiro, Luís

The radical cystectomy and urinary diversion have a significant negative impact on quality of life, essentially because it causes deterioration of sexual and urinary functions. The possibility to offer a surgery that preserves female pelvic organs has been proposed in selected cases and it seems to improve the functional outcomes without compromising the oncologic outcomes. Here, we present a clinical case of a...

Date: 2024   |   Origin: Acta Urológica Portuguesa

Novel Oxygen- and Curcumin-Laden Ionic Liquid@Silica Nanocapsules for Enhanced ...

Henriques, Joana F.; Pina, João; Braga, Mara E. M.; Dias, Ana M. A.; Coimbra, Patrícia; Sousa, Herminio C. de

The efficiency of photodynamic therapy is often limited by the scarcity of oxygen at the target site. To address this problem, this work proposes the development of a new nanosystem for antimicrobial photodynamic therapy applications (aPDT) where the natural-origin photosensitizer curcumin (CUR) is immersed in an oxygen-rich environment. Inspired by the perfluorocarbon-based photosensitizer/O2 nanocarriers repo...


Investigating the photophysical properties and biological efficacy of BODIPY de...

Gonçalves, Raquel Costa Raínha; Pinto, Sónia Catarina Silva; Pina, João; Gomes-da-Silva, Lígia C.; Costa, Susana P. G.; Raposo, M. Manuela M.

The selectivity of photosensitizers for light activation is a key advantage in photodynamic therapy (PDT), allowing for precise targeting while sparing healthy cells. BODIPY derivatives have emerged as promising PDT candidates due to their tunable photophysical properties and versatile synthesis. Herein, we explore the photophysical characterization and the in vitro photodynamic activity of BODIPY analogues mes...



Ring-Fused meso-Tetraarylchlorins as Auspicious PDT Sensitizers: Synthesis, Str...

Laranjo, Mafalda; Pereira, Nelson A. M.; Oliveira, Andreia S. R.; Aguiar, Márcia Campos; Brites, Gonçalo Sousa; Nascimento, Bruno F. O.

Novel 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-fused meso-tetraarylchlorins, with different degrees of hydrophilicity (with methyl ester, hydroxymethyl, and carboxylic acid moieties), have been synthesized and their photophysical characterization as well as in vitro photocytotoxicity assessment against human melanoma and esophageal and bladder carcinomas was carried out. An integrated analysis of the photosens...


Construction of a radiofrequency wireless system for electric energy transmission

Romba, Luis; Baikova, Elena; Pina, João; Mescheryakov, Viktor; Valtchev, Stanimir; Melício, Rui; Grachieva, El.

ТНE PURPOSE. The objective of this study is to investigate the possibilities of longer distance resonant energy transmission applying Wireless Power Transfer (WPT) in the MHz frequency range. The planned final purpose is the energy to be transferred to all types (aerial and terrestrial) of electric vehicles (EV), mainly for the battery charging at a larger distance, compared to the normal dis-tances of WPT in u...



Competências emocionais: estratégias facilitadoras na promoção da prática de en...

Costa, Cátia Sofia Afonso; Pina, João; Galvão, Ana Maria; Rodríguez-Escanciano, Susana

Perante as exigências constantes e contínuas dos diferentes ambientes da prática de cuidados, bem como, a presença de clientes mais des(informados), levam a que os enfermeiros se encontrem munidos de um conjunto de competências emocionais que facilitem as suas intervenções, através de uma melhor e mais adequada compreensão das reais necessidades dos clientes. Estas competências emocionais, essencialmente dividi...

Date: 2021   |   Origin: Biblioteca Digital do IPB

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