110 documents found, page 1 of 11
Ionic liquid-based nanoemulsion as a promising strategy to enhance the bioacces...
Sousa, Vítor; Lüdtke, Fernanda Luisa; Hijo, Ariel A. C. Toledo; Loureiro, Luís; Dias, Oscar; Vicente, A. A.; Pinheiro, A. C.; Geada, PedroDunaliella salina is a unicellular halophile green microalga that presents the capacity to accumulate high amounts of β-carotene, a bioactive compound widely recognized by its health benefits. To fulfil its biological functions, however, β-carotene needs to be bioaccessible, which is challenging as its bioaccessibility is typically low. A promising strategy to overcome β-carotene's low bioaccessibility is its e...
In vitro digestion and cytotoxicity study of cannabidiol-loaded nanostructured ...
Vardanega, Renata; Lüdtke, Fernanda Luisa; Loureiro, Luís; Gonçalves, Raquel F. S.; Martins, Joana T.; Pinheiro, A. C.; Vicente, A. A.Cannabidiol (CBD), a lipophilic compound with promising health benefits, such as analgesic, anti-inflammatory and neuroprotective effects, is characterized by low oral bioavailability, which limit its therapeutic application. To address these limitations, CBD was incorporated into nanostructured lipid carriers (NLCs), either as CBD-rich extract (CBDext) or as an isolate (CBDiso). The resulting systems NLC-CBDex...
Impact of the physiological stage on the bioaccessibility of α-tocopherol from ...
Fernandes, Jean Michel; Ménard, Olivia; Cochet, Marie-Françoise; Ossemond, Jordane; Vicente, A. A.; Pinheiro, A. C.; Dupont, DidierAge-related physiological decline negatively impacts nutrient digestion and absorption, making older adults more susceptible to diet-related diseases. Fortified and functional foods are promising strategies to enhance the delivery of nutraceuticals and bioactive compounds. However, understanding how these foods behave under age-specific gastrointestinal conditions is essential. Despite the relevance of in vitro...
Development of 3D-printed foods incorporating riboflavin-loaded whey protein is...
Araújo, João Miguel Fernandes; Fernandes, Jean Michel; Madalena, Daniel Alexandre Silva; Gonçalves, Raquel Filipa Silva; Vieira, Jorge Miguel Magalhães3D printing has emerged as a groundbreaking technology, aiming to enhance sensory attributes and improving nutritional/functional aspects. Simultaneously, nano-delivery systems have emerged as an opportunity to protect bioactive compounds against degradation and improve their bioaccessibility. Therefore, a novel concept is underway, involving the 3D printing of perishable healthy foods previously fortified with...
Development of novel functional thickened drinks enriched with vitamin D3 for t...
Fernandes, Jean Michel; Vieira, Jorge Miguel Magalhães; Gonçalves, Raquel Filipa Silva; Martins, Joana T.; Vicente, A. A.; Pinheiro, A. C.The older adult population is greatly affected by malnutrition. This condition can arise from inappropriate micro and micronutrient intake, as well as due to experienced age-related changes. For instance, a significant number of older adults suffer from dysphagia. Thus, the development of foods with adequate consistency/viscosity are vital for overcome this condition. Within this framework, novel functional thi...
Symbiotic honey beverages: a matrix which tells a story of survival and protect...
Pinto Neto, Walter de Paula; Lucena, Thays Maria Costa de; Paixão, Giselle Alves da; Shinohara, Neide Kazue Sakugawa; Pinheiro, A. C.; Vicente, A. A.This review provides an overview of how probiotic honey beverages have been used by humankind throughout history to promote protection of human health. After a brief historical explanation with the main reports involving the use of these beverages for medicinal and conservation purposes, their symbiotic effects and the main physicochemical and microbiological properties reported as benefiting this synergistic e...
Potential prebiotic effect of Caatinga bee honeys from the Pajeú hinterland (Pe...
Pinto-Neto, Walter de Paula; Loureiro, Luís Carlos Sá; Gonçalves, Raquel Filipa Silva; Marques, Márcia Cristina Teixeira; Rodrigues, Rui Miguel MartinsThe singular biodiversity of the Brazilian Caatinga inspires innovative solutions in food science. In this study, we evaluated the prebiotic potential of honeys produced by Apis mellifera in the Pajeú hinterland, Pernambuco, Brazil (Caatinga Biome), with different floral origins: Mastic (Aroeira), Mesquite (Algaroba), and mixed flowers. These were used to formulate synbiotic and alcoholic beverages fermented by...
Co-encapsulation of vitamin D3 and curcumin in plant protein-based nanoemulsion...
Marques, Márcia; Gonçalves, Raquel Filipa Silva; Madalena, Daniel Alexandre Silva; Abrunhosa, Luís; Vicente, A. A.; Pinheiro, A. C.This study aimed to develop plant-based nanoemulsions (NE) for co-encapsulation of vitamin D3 and curcumin, comparing the emulsifying properties of pea and potato proteins. Different oil and protein concentrations were tested, and formulations with the smallest particle size were characterized and submitted to harmonized static in vitro digestion. Formulations prepared with the highest protein concentration (10...
Development of chitosan/navy bean extract-based nanocarriers for oral delivery ...
Oliveira Júnior, Fernando Divino; Pinheiro, A. C.; Vicente, A. A.; Cunha, Rosiane LopesStrategies have been developed for insulin administration to treat diabetes. In this sense, insulin vehiculation in nanoparticles could effectively protect this bioactive against digestion conditions and allow its intestinal absorption. To exhibit such features, it is essential to choose the materials that will compose the nanoparticles adequately. This study employed genipin-mediated crosslinking of chitosan (...
Enhancing cannabidiol bioaccessibility using ionic liquid as emulsifier to prod...
Vardanega, Renata; Lüdtke, Fernanda Luisa; Loureiro, Luís Carlos Sá; Hijo, Ariel A. C. Toledo; Martins, Joana T.; Pinheiro, A. C.; Vicente, A. A.The emulsifying potential of a biocompatible ionic liquid (IL) to produce lipid-based nanosystems developed to enhance the bioaccessibility of cannabidiol (CBD) was investigated. The IL (cholinium oleate) was evaluated at concentrations of 1 % and 2 % to produce nanoemulsions (NE-IL) and nanostructured lipid carriers (NLC-IL) loaded with CBD. The IL concentration of 1 % demonstrated to be sufficient to produce ...