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Enteropathogenic Escherichia coli Infection Induces Diarrhea, Intestinal Damage...

Ledwaba, Solanka E.; Costa, Deiziane V. S.; Bolick, David T.; Giallourou, Natasa; Medeiros, Pedro H. Q. S.; Swann, Jonathan R.; Traore, Afsatou N.

Enteropathogenic E. coli (EPEC) are recognized as one of the leading bacterial causes of infantile diarrhea worldwide. Weaned C57BL/6 mice pretreated with antibiotics were challenged orally with wild-type EPEC or escN mutant (lacking type 3 secretion system) to determine colonization, inflammatory responses and clinical outcomes during infection. Antibiotic disruption of intestinal microbiota enabled efficient ...

Date: 2021   |   Origin: Oasisbr

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