14 documents found, page 1 of 2
Omega-3 fatty acids from fish by-products: innovative extraction and applicatio...
Rodrigues, Matilde; Rosa, Ana; Almeida, André; Martins, Rui; Ribeiro, Tânia; Pintado, Manuela; Gonçalves, Raquel F. S.; Pinheiro, Ana C.Omega-3 fatty acids (O3FA) are essential nutrients that play a crucial role in maintaining human and animal health. They are known for their numerous health claims, including cardiovascular benefits, contributing to both the prevention and treatment of immunological, neurological, reproductive, and cardiovascular complications, and supporting overall well-being. Fish, especially oily fish, comprise rich source ...
Gelatin-based nanocomposite films activated by double emulsion loaded with “Pit...
Tessaro, Larissa; Gonçalves, Raquel Filipa Silva; Martins, Joana T.; Pinheiro, Ana C.; Vicente, António A.; Sobral, Paulo J. A.The main aim of this study was to carry out an in vitro digestion of gelatin-based films and nanocomposite films activated with Pitanga (Eugenia uniflora L.) leaf extract (PLE) encapsulated in a W/O/W double emulsion. Also, the effects of encapsulation and addition of crystalline nanocellulose on PLE bioaccessibility, and on Caco-2 cells viability, after in vitro digestion, were evaluated. The free PLE, W/O (SE...
Omega-3 fatty acids from fish by-products: Innovative extraction and applicatio...
Rodrigues, Matilde; Rosa, Ana; Almeida, André; Martins, Rui; Ribeiro, Tânia; Pintado, Manuela; Gonçalves, Raquel F.S.; Pinheiro, Ana C.Omega -3 fatty acids (O3FA) are essential nutrients that play a crucial role in maintaining human and animal health. They are known for their numerous health claims, including cardiovascular benefits, contributing to both the prevention and treatment of immunological, neurological, reproductive, and cardiovascular complications, and supporting overall well-being. Fish, especially oily fish, comprise rich source...
Assessing the in vitro digestion of lactoferrin-curcumin nanoparticles using th...
Madalena, Daniel A.; Araújo, João F.; Ramos, Óscar L.; Vicente, António A.; Pinheiro, Ana C.Nanosized delivery systems have been the subject of research and discussion in the scientific community due to their unique properties and functionality. However, studies reporting the behaviour of nanodelivery systems under dynamic in vitro digestion conditions are still very scarce. To address this gap, this study aims to assess the dynamic in vitro gastric digestion of lactoferrin/curcumin nanoparticles in t...
Two-step purification of epilactose produced by cellobiose 2-epimerase from Cal...
Cardoso, Beatriz B.; Fernandes, Jean Michel; Pinheiro, Ana C.; Braga, Adelaide Correia; Silvério, Sara Isabel Cruz; Rodrigues, L. R.Epilactose is a functional sugar that can be produced from lactose using cellobiose 2-epimerase and it is considered a developing prebiotic. In that sense, the development of strategies to produce and purify epilactose is key for its wider use in the food industry. The aim of this work was to establish a food-grade purification strategy suitable to be scaled-up to an industrial level. Firstly, the epilactose wa...
Emerging challenges in assessing bio-based nanosystems’ behaviour under in vitr...
Madalena, Daniel; Fernandes, Jean; Avelar, Zita; Gonçalves, Raquel; Ramos, Óscar L.; Vicente, António A.; Pinheiro, Ana C.The current consumers’ demand for high quality food products together with the growing awareness regarding the link between health and nutrition has led to the development of novel food products with added functionality. Such functionality can be modulated by adding bio-based nanosystems that can improve the bioaccessibility of bioactive compounds and facilitate nutrient absorption. However, these functional pr...
In vitro digestion and bioaccessibility studies of vitamin E-loaded nanohydroxy...
Ribeiro, Andreia; Gonçalves, Raquel F.S.; Pinheiro, Ana C.; Manrique, Yaidelin A.; Barreiro, M.F.; Lopes, José Carlos B.; Dias, Madalena M.Vitamin E is a lipophilic vitamin playing an essential role in human health. Due to oxidative instability, it presents fast degradation and bioactivity loss. In this study, vitamin E-loaded Pickering emulsions (PEs) stabilized by nano-hydroxyapatite (n-HAp) were produced using a static mixer (NETmix), a technique enabling continuous production and droplet size tailoring. Thus, oil-in-water (O/W) emulsions conta...
β-lactoglobulin micro- and nanostructures as bioactive compounds vehicle: In vi...
Simões, Lívia S.; Martins, Joana T.; Pinheiro, Ana C.; Vicente, António A.; Ramos, Oscar. L.β-Lactoglobulin (β-Lg) is known to be capable to bind hydrophilic and hydrophobic bioactive compounds. This research aimed to assess the in vitro performance of β-Lg micro- (diameter ranging from 200 to 300 nm) and nano (diameter < 100 nm) structures associated to hydrophilic and hydrophobic model compounds on Caco-2 cells and under simulated gastrointestinal (GI) conditions. Riboflavin and quercetin were studi...
Influence of emulsifier type on in vitro digestion of curcumin nanoemulsions: l...
Gonçalves, Raquel Filipa Silva; Martins, Joana Teresa Rodrigues; Vicente, A. A.; Pinheiro, Ana C.Curcumin is a polyphenol with several health benefits such as antimicrobial, anti-oxidant, anti-tumoral and anti-inflammatory activities. Although this bioactive compound is present in several food products as spice or colorant, it has poor solubility in aqueous solutions and low bioavailability. Nanoemulsions (NE) are a colloidal delivery system which can improve the bioavailability and stability of lipophilic...
Lactoferrin-based nanoparticles as a vehicle for iron in food applications: dev...
Martins, Joana; Santos, Susana Fernandes dos; Bourbon, Ana Isabel Juncá Sottomayor Lisboa; Pinheiro, Ana C.; González-Fernández, ÁfricaThis study aims at developing and characterizing bovine lactoferrin (bLf) nanoparticles as an iron carrier. bLf nanoparticles were characterized in terms of size, polydispersity index (PdI), electric charge (-potential), morphology, structure and stability over time. Subsequently, iron release experiments were performed at different pH values (2.0 and 7.0) at 37 °C, in order to understand the release mechanism....