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Purple Biodeterioration in Parchment: a Case in the Alcobacense Collection

Pinheiro, C; Miller, A; Bhattacharya, S; Vaz, P; Caldeira, A Teresa; Casanova, C

The understanding of purple biodeterioration, or the appearance of purple tinged stains in parchment, has seen a sharp evolution in the last few years. Modern molecular analysis of the DNA, using Next-Generation Sequencing, have made it possible to hypothesize a chain of events triggered by the presence of Archaeobacteria in the parchment, a succession theory that builds on the presence of complex biological co...


The Relevance of Plant-Based Diets and Micronutrient Supplementation for Body C...

Pinheiro, C; Silva, F; Rocha, I; Martins, C; Giesteira, L; Dias, B; Lucas, A; Alexandre, AM; Ferreira, C; Viegas, B; Bracchi, I; Guimarães, J; Amaro, J

"Objectives: This study aimed to compare the anthropometry and body composition of vegetarian and omnivorous adults living in Portugal, while exploring nutritional and health parameters underlying observed differences. Methods: 425 omnivorous (OMNI), lacto-ovo-vegetarian (LOV), or vegan (VEG) healthy adults were recruited. Anthropometry was measured, and bioelectrical impedance analysis was performed. Participa...


Underneath the Purple Stain

Pinheiro, C; Miller, A; Vaz, P; Caldeira, A T; Casanova, C

The Alcobacenses are one of the most important Portuguese collections of Monastic codices. During a campaign study to further advance our knowledge on this important legacy and its state of conservation, a heavily deteriorated codex (ALC.338) stood out due to the presence of purple stains on the lower margins on virtually all folios. In some of them, the purple stains are accompanied by yellow and brown patches...


Noncompliance to iodine supplementation recommendation is a risk factor for iod...

Matta Coelho, CM; Guimaraes, J; Bracchi, I; Xavier Moreira, NX; Pinheiro, C; Ferreira, P; Pestana, D; Barreiros Mota, IB; Cortez, A; Prucha, C

Purpose After a recommendation for iodine supplementation in pregnancy has been issued in 2013 in Portugal, there were no studies covering iodine status in pregnancy in the country. The aim of this study was to assess iodine status in pregnant women in Porto region and its association with iodine supplementation. Methods A cross-sectional study was conducted at Centro Hospitalar Universitário São João, Porto, f...


The association of milk and dairy consumption with iodine status in pregnant wo...

Ferreira, P; Pinheiro, C; Matta Coelho, C; Guimarães, J; Pereira, G; Xavier Moreira, N; Cortez, A; Bracchi, I; Pestana, D; Barreiros Mota, I; Prucha, C

The role of milk and dairy products in supplying iodine to pregnant women is unknown in Portugal. The aim of this study was to evaluate the association between milk and dairy product consumption and the iodine status of pregnant women in the IoMum cohort of the Oporto region. Pregnant women were recruited between 10 and 13 weeks of gestation, when they provided a spot urine sample and information on lifestyle a...


Iodine knowledge is associated with iodine status in Portuguese pregnant women:...

Pinheiro, C; Xavier, Moreira, N; Ferreira, P; Matta, Coelho, C; Guimarães, J; Pereira, G; Cortez, A; Bracchi, I; Pestana, D; Barreiros, Mota, I

Lack of knowledge about iodine has been suggested as a risk factor for iodine deficiency in pregnant women, but no studies have addressed this issue in Portugal. So, the aim of this study was to investigate iodine knowledge among Portuguese pregnant women and its association with iodine status. IoMum, a prospective observational study, included 485 pregnant women recruited at Centro Hospitalar e Universitário d...


Palliative splenic irradiation for symptomatic splenomegaly in non-Hodgkin lymp...

Oliveira, LC; Fardilha, C; Louro, M; Pinheiro, C; Sousa, A; Marques, H; Costa, P

INTRODUCTION AND AIMS: Splenic marginal zone lymphoma, an uncommon subtype of non-Hodgkin lymphoma (NHL), is usually present with symptomatic splenomegaly. Although splenectomy has long been considered the first-line therapy in symptomatic or cytopenic patients, it can lead to significant morbidity and mortality. Splenic irradiation is an option for patients who have a poor response to systemic therapy and/or a...


Neurocognitive profiles in adolescents and young adults with congenital heart d...

Areias, ME; Peixoto, B; Santos, I; Cruz, L; Regadas, A; Pinheiro, C; Monteiro, H; Araújo, S; Carvalho, T; Miranda, J; Moura, C; Soares, J; Viana, Victor

Introduction and Objectives: The objectives of this study were to assess the neuropsychological performance (NP) of adolescents and young adults with congenital heart disease (CHD), comparing them with a group of healthy controls, to determine whether there are different neurocognitive phenotypes in CHD, and to identify their relation to sociodemographic, neonatal, clinical and psychological adjustment variable...


Stepwise strategy to improve cervical cancer screening adherence (SCAN-Cervical...

Firmino-Machado, J; Varela, S; Mendes, R; Moreira, A; Lunet, N; Carmo, A; Cancela, A; Firmino, A; Ramos, A; Teixeira, A; Vieira, A; Badim, B; Tojal, C

The aim of this study was to test the effectiveness of invitation to cervical cancer screening through a very low-cost strategy based on automated and customized text messages, phone calls and reminders. A randomized (1:1) controlled trial was conducted among 13 Portuguese primary care units, recruiting women aged 25 to 49 years, eligible for cervical cancer screening, with an available mobile phone number. In ...


Alkali-activated cement using slags and fly ash

Rios, S; Viana da Fonseca, AV; Pinheiro, C; Sandra Nunes; Cristelo, N

Alkali Activated Cements (AAC) are a very convenient alternative to common binders as waste materials like slag and fly ash are included in their production. In this paper, a response surface method is used to optimize an AAC made with fly ash, steel slag, sodium silicate and sodium hydroxide. For this purpose, an experimental plan contemplating 26 mixtures was developed, which included compression and flexural...


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