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The impact of self-stigma in people with diagnosis of severe mental illness: a ...

Pinto, AS; Almada, M; Fonseca, I; Sousa, A; Lopes, A

"Introduction Self-stigma refers to the process in which a person internalizes negative stereotypes, beliefs, and prejudices about their mental illness, adopting a stigmatized view of themselves. Severe mental illness is one of the most socially exclusive stigmata and is associated with poor clinical and functional outcomes and social withdrawal. Objectives In Portugal, investigation regarding self-stigma is sc...


Prognostic Value of Isolated Elevated Troponin I Levels in Patients without Acu...

Domingues, C; Ferreira, MJ; Ferreira, JM; Marinho, AV; Alves, PM; Ferreira, C; Fonseca, I; Gonçalves, L

Background: Although non-ischemic troponin elevation is frequently seen in patients admitted to the emergency department (ED), consensus regarding its management is lacking. Objectives: This study aimed to characterize patients admitted to the ED with non-ischemic troponin elevation and to identify potential mortality predictors in this population. Methods: This retrospective observational study included ED pat...


Different kidney function trajectory patterns before dialysis in elderly patien...

Santos, J; Oliveira, P; Severo, M; Lobato, L; Cabrita, A; Fonseca, I

Background. Identifying trajectories of kidney disease progression in chronic kidney disease (CKD) patients may help to deliver better care. We aimed to identify and characterize trajectories of renal function decline in CKD patients and to investigate their association with mortality after dialysis.Methods. This retrospective cohort study included 378 CKD patients who initiated dialysis (aged 65 years and over...



Predicting 6-Month Mortality in Incident Elderly Dialysis Patients: A Simple Pr...

Santos, J; Oliveira, P; Malheiro, J; Campos, A; Correia, S; Cabrita, A; Lobato, L; Fonseca, I

Aim: Mortality in end-stage renal disease (ESRD) remains high, particularly among elderly, who represents the most rapidly growing segment of the ESRD population in wealthier countries. We developed and validated a risk score in elderly patients to predict 6-month mortality after dialysis initiation. Methods: We used data from a cohort of 421 patients, aged 65 years and over who started dialysis between 2009 an...


Tungstophosphoric acid immobilised in SBA-15 as an efficient heterogeneous acid...

Castanheiro, J; Fonseca, I; Ramos, A; Vital, J

Alkoxylation of α−pinene, β−pinene and limonene was performed in the presence of SBA-15-occluded tungstophosphoric acid (HPW). The HPW was immobilised in SBA-15 using the sol-gel method. The catalysts were characterised by N2 adsorption, FT-IR, Raman spectroscopy, X-Ray diffraction, ICP-AES and TEM. A series of catalysts with different heteropolyacid loadings ranging from 1.8 to 19.3 wt. % were prepared. PW4-SB...


The association between 25(OH)D levels, frailty status and obesity indices in o...

Sousa Santos, AR; Afonso, Cláudia; Santos, Alejandro; Borges, Nuno; Moreira, Pedro; Padrão, Patrícia; Fonseca, I; Amaral, Teresa

Background Vitamin D deficiency is common in older adults and has been linked with frailty and obesity, but it remains to be studied whether frail obese older adults are at higher risk of vitamin D deficiency. Therefore, the aim of this study is to explore the association between frailty, obesity indices and serum 25(OH)D concentrations. Methods 1447 individuals with 65 years or older, participating in a cross-...


Incorporating Scoring Risk Models for Care Planning of the Elderly with Chronic...

Santos, J; Fonseca, I

Mortality in chronic kidney disease remains high, particularly among the elderly, who represent the most rapidly growing segment of the end-stage renal disease population in wealthier countries. The management of older adults with chronic kidney disease has become a clinical challenge, and care for those patients expected to progress to end-stage renal disease should focus on evaluating the overall benefit of o...


Psychopathological dimensions in subjects with hereditary ATTR V30M amyloidosis...

Lopes, A; Fonseca, I; Sousa, A; Rodrigues, C; Branco, M; Coelho, T; Sequeiros, J; Freitas, P

Background: Chronic physical illness has been associated with emotional distress. Chronic diseases may change usual family patterns with economic, social and family losses. Hereditary ATTR V30M amyloidosis is a rare, fatal inherited systemic amyloidosis, with chronic evolution and beginning in adulthood. Aims and methods: To evaluate psychopathological dimensions and how they correlated with disease-related lif...


Family dynamics in transthyretin-related familial amyloid polyneuropathy Val30M...

Lopes, A; Rodrigues, C; Fonseca, I; Sousa, A; Branco, M; Coelho, T; Sequeiros, J; Freitas, P

Adult-onset, chronic, genetic diseases like transthyretin-related familial amyloid polyneuropathy Val30Met (TTR-FAP Val30Met), have a major psychosocial impact not only on patients, but also on families. Genetic risk may therefore be an increased factor in psychosocial impact of the disease on these families' functioning. To evaluate impact of genetic risk, a study was conducted to perceive the impact of the il...


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