10 documents found, page 1 of 1
Zinc/magnesium ferrite nanoparticles functionalized with silver for optimized p...
Fernandes, Ricardo Jorge Cunha; Cardoso, Beatriz D.; Rodrigues, Ana Rita Oliveira; Pires, Ana; Pereira, André M.; Araújo, João P.; Pereira, LucianaWater pollution is a major environmental challenge. Due to the inefficiency of conventional wastewater treatment plants in degrading many organic complex compounds, these recalcitrant pollutants end up in rivers, lakes, oceans and other bodies of water, affecting the environment and human health. Semiconductor photocatalysis is considered an efficient complement to conventional methods, and the use of various n...
Development of pH-Sensitive magnetoliposomes containing shape anisotropic nanop...
Pacheco, Ana Rita F.; Cardoso, Beatriz D.; Pires, Ana; Pereira, André M.; Araújo, João P.; Carvalho, Violeta M.; Rodrigues, Raquel O.Late diagnosis and systemic toxicity associated with conventional treatments make oncological therapy significantly difficult. In this context, nanomedicine emerges as a new approach in the prevention, diagnosis and treatment of cancer. In this work, pH-sensitive solid magnetoliposomes (SMLs) were developed for controlled release of the chemotherapeutic drug doxorubicin (DOX). Shape anisotropic magnetic nanopar...
Magnetoliposomes containing multicore nanoparticles and a new antitumor thienop...
Lopes, Fábio A. C.; Fernandes, André V. F.; Rodrigues, Juliana M.; Queiroz, Maria João R. P.; Almeida, B. G.; Pires, Ana; Pereira, André M.Multicore magnetic nanoparticles of manganese ferrite were prepared using carboxymethyl dextran as an agglutinating compound or by an innovative method using melamine as a cross-coupling agent. The nanoparticles prepared using melamine exhibited a flower-shape structure, a saturation magnetization of 6.16 emu/g and good capabilities for magnetic hyperthermia, with a specific absorption rate (SAR) of 0.14 W/g. M...
Plasmonic/magnetic liposomes based on nanoparticles with multicore-shell archit...
Rodrigues, Ana Rita Oliveira; Santos, Lia C. A.; Macedo, Daniela O.; Rio, Irina Soraia Rainho; Pires, Ana; Pereira, André M.; Araújo, João PedroMultifunctional nanosystems are capable to carry one or more therapeutic agents (thermal and/or targeting agents and chemotherapeutic drugs), offering the capability to concurrently perform different treatment modalities using a single nanosystem. Cluster nanostructures, consisting of densely packed aggregates of magnetic nanoparticles, have shown enhanced heating capabilities. Their combination with plasmonic ...
Development of thermo-and pH-sensitive liposomal magnetic carriers for new pote...
Ribeiro, Beatriz C.; Alvarez, Cristina A.R.; Alves, Bárbara C.; Rodrigues, Juliana M.; Queiroz, Maria João R. P.; Almeida, B. G.; Pires, AnaThe development of stimuli-sensitive drug delivery systems is a very attractive area of current research in cancer therapy. The deep knowledge on the microenvironment of tumors has supported the progress of nanosystems’ ability for controlled and local fusion as well as drug release. Temperature and pH are two of the most promising triggers in the development of sensitive formulations to improve the efficacy of...
Magnetoliposomes based on magnetic/plasmonic nanoparticles loaded with tricycli...
Rio, Irina Soraia Rainho; Rodrigues, Ana Rita Oliveira; Rodrigues, Juliana M.; Queiroz, Maria João R. P.; Calhelha, R. C.; Ferreira, Isabel C. F. R.Liposome-like nanoarchitectures containing manganese ferrite nanoparticles covered or decorated with gold were developed for application in dual cancer therapy, combining chemotherapy and photothermia. The magnetic/plasmonic nanoparticles were characterized using XRD, UV/Visible absorption, HR-TEM, and SQUID, exhibiting superparamagnetic behavior at room temperature. The average size of the gold-decorated nanop...
Magnetoliposomes based on magnetic/plasmonic nanoparticles loaded with tricycli...
Rio, Irina S.R.; Rodrigues, Ana Rita O.; Rodrigues, Juliana M.; Queiroz, Maria João R.P.; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.Liposome-like nanoarchitectures containing manganese ferrite nanoparticles covered or decorated with gold were developed for application in dual cancer therapy, combining chemotherapy and photothermia. The magnetic/plasmonic nanoparticles were characterized using XRD, UV/Visible absorption, HR-TEM, and SQUID, exhibiting superparamagnetic behavior at room temperature. The average size of the gold-decorated nanop...
Enhanced thermoelectric properties of Sb<inf>2</inf>Te<inf>3</inf> and Bi<inf>2...
Vieira, E. M. F; Figueira, Joana; Pires, Ana L.; Grilo, José; Silva, Manuel Fernando Ribeiro; Pereira, André M.; Gonçalves, L. M.Improved thermoelectric properties of p-Sb2Te3 and n-Bi2Te3 films deposited by thermal co-evaporation at 503 K and 543 K, respectively, are reported, by using two types of substrate (borosilicate glass and 25 μm - Kapton® polyimide). Seebeck coefficients of 194 μV K−1 and - 233 μV K−1 and electrical conductivities of 3.2 × 104 (Ω m)−1 and 5.0 × 104 (Ω m)−1, lead to optimized power factors of 1.2 × 10−3 W K−2 m−...
Development of multifunctional liposomes containing magnetic/plasmonic MnFe2O4/...
Rodrigues, Ana Rita Oliveira; Matos, Joana O. G.; Dias, Armando M. Nova; Almeida, B. G.; Pires, Ana; Pereira, André M.; Araújo, João P.Multifunctional liposomes containing manganese ferrite/gold core/shell nanoparticles were developed. These magnetic/plasmonic nanoparticles were covered by a lipid bilayer or entrapped in liposomes, which form solid or aqueous magnetoliposomes as nanocarriers for simultaneous chemotherapy and phototherapy. The core/shell nanoparticles were characterized by UV/Visible absorption, X-Ray Diffraction (XRD), Transmi...
Magnetoliposomes as carriers for promising antitumor thieno[3,2-b]pyridin-7-ary...
Rodrigues, Ana Rita O.; Almeida, Bernardo G.; Rodrigues, Juliana M.; Queiroz, Maria João R.P.; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Pires, A.Magnetoliposomes containing superparamagnetic manganese ferrite nanoparticles were tested as nanocarriers for two new promising antitumor drugs, a N-(3-methoxyphenyl)thieno[3,2-b]pyridin-7-amine (1) and a N-(2-methoxy-phenyl)thieno[3,2-b] pyridin-7-amine (2). The fluorescence emission of both compounds was studied in different polar and non-polar media, evidencing a strong intramolecular charge transfer charact...