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Rewired glycosylation activity promotes scarless regeneration and functional re...

Nogueira-Rodrigues, Joana; Leite, Sérgio C.; Pinto-Costa, Rita; Sousa, Sara C.; Luz, Liliana L.; Sintra, Maria A.; Oliveira, Raquel; Monteiro, Ana C.

Regeneration of adult mammalian central nervous system (CNS) axons is abortive, resulting in inability to recover function after CNS lesion, including spinal cord injury (SCI). Here, we show that the spiny mouse (Acomys) is an exception to other mammals, being capable of spontaneous and fast restoration of function after severe SCI, re-establishing hind limb coordination. Remarkably, Acomys assembles a scarless...


Cell–fibronectin interactions and actomyosin contractility regulate the segment...

Gomes De Almeida, Patrícia; Rifes, Pedro; Jesus, Ana Patrícia; Pinheiro, Gonçalo; P. Andrade, Raquel; Thorsteinsdóttir, Sólveig

Fibronectin is essential for somite formation in the vertebrate embryo. Fibronectin matrix assembly starts as cells emerge from the primitive streak and ingress in the unsegmented presomitic mesoderm (PSM). PSM cells undergo cyclic waves of segmentation clock gene expression, followed by Notch-dependent upregulation of meso1 in the rostral PSM which induces somite cleft formation. However, the relevance of the ...


Scene reconstruction for storytelling in 360º videos

Pinheiro, Gonçalo; Alves, Nelson; Magalhães, Luís Gonzaga Mendes; Agrellos, Luís; Guevara, Miguel

In immersive and interactive contents like 360-degrees videos the user has the control of the camera, which poses a challenge to the content producer since the user may look to where he wants. This paper presents the concept and first steps towards the development of a framework that provides a workflow for storytelling in 360-degrees videos. With the proposed framework it will be possible to connect a sound to...


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