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Neuroinflammatory Biomarkers in Chronic Low Back Pain

Pinheiro, João; Lima, Pedro; Pestana, Ricardo; Sousa, Miriam; Alves, José; Ribeiro, Hugo; D’Almeida, Gonçalo Neto; Santana, Isabel

Background: Chronic low back pain (CLBP) is a leading cause of disability worldwide and remains clinically challenging due to its marked heterogeneity and limited correlation between structural pathology and symptoms. Increasing evidence suggests that neuroinflammatory mechanisms and central sensitization (CS) contribute to pain persistence in a clinically relevant subset of patients. This narrative review crit...


Aging and Medical Rehabilitation: A Contribution to a Comprehensive Discussion

Pinheiro, João; Rovisco Branquinho, Lurdes; Branco, João; Costa, Joana; Coimbra, António; Aguiar Branco, Catarina; Nunes, Renato

The rapid development of innovative technologies is transforming the landscape of elderly care and physical and rehabilitation medicine, addressing the unique challenges of aging. This document explores cutting-edge solutions, including smart house technologies (SHT), artificial intelligence (AI), virtual reality (VR), robotics, and advanced geriatric rehabilitation (GR) assessment strategies. These advancement...


Precision Medicine in Physical and Rehabilitation Medicine (PRM)

Pinheiro, João; Branco, João; Aguiar-Branco, Catarina; Laíns, Jorge; Zão, Ana; Nunes, Renato; Campos, Inês

Precision Rehabilitation (PR) represents a transformative approach in Physical and Rehabilitation Medicine (PRM), emphasizing the integration of personalized care with the best clinical evidence to enhance patient outcomes. This article discusses the pivotal role of emerging technologies such as Big Data (BD) and Artificial Intelligence (AI) in revolutionizing rehabilitation practices. By leveraging vast datase...


Skeletal maturity in adolescence: evaluating bone development and age metrics

Pinheiro, João; Ribeiro, Luís; Teixeira, Diana; Magalhães Ribeiro, Anabela de; Coelho-e-Silva, Manuel João

Background/Objectives: Bone maturation and development are crucial for growth and development, especially in children and adolescents; however, some qualitative methods, such as Greulich & Pyle, do not provide accurate data. Our aim is to verify whether skeletal age (SA) can predict and correlate with bone mineral content (BMC), bone mineral density (BMD), and body composition (BC). Methods: A cross-sectional s...


Skeletal Maturity in Adolescence

Pinheiro, João; Ribeiro, Luís Pedro; Teixeira, Diana; Magalhães Ribeiro, Anabela; Coelho-e-Silva

Publisher Copyright: © 2025 by the authors.; Background/Objectives: Bone maturation and development are crucial for growth and development, especially in children and adolescents; however, some qualitative methods, such as Greulich & Pyle, do not provide accurate data. Our aim is to verify whether skeletal age (SA) can predict and correlate with bone mineral content (BMC), bone mineral density (BMD), and body c...


Investigação em Medicina Física e Reabilitação: Aspectos Actuais

Pinheiro, João; Rovisco Branquinho, Lurdes; Ribeiro, Flávio; Branco, João; Laíns, Jorge; Aguiar Branco, Catarina; Cantista, Pedro

aa; Research in rehabilitation is a multidisciplinary field that focuses on the assessment, treatment, and support of individuals with disabilities, activity limitations, and participation restrictions, with the aim of improving their functionality and quality of life. Science and research in PRM are relatively young, like the specialty, and have some peculiar challenges and specificities. The methodology of re...


Cork Quality and Density Assessment – A Pilot Study Using Computerized Tomography

Pinheiro, João; Abrantes, António; Brito, Gilmar

Cork is a natural, renewable, sustainable raw material that has been used for many centuries and the products obtained from cork bark represent an important economic resource for several countries. Quality control is performed in several steps, however, most of these controls are visual checks performed by experienced people. The quality control of cork stoppers is mandatory to guarantee the perfect conservatio...


Interpretation of many-valuedness in quality-of-life instruments

Ribeiro, Luís Pedro; Eklund, Patrik; Gomes Alves Ferreira, Maria Augusta; Magalhães Ribeiro, Anabela de; Farinha, Maria Conceição; Paiva, Maria Adelaide

Assessment instruments for functioning in general and quality of life in particular often involve discrete scales with three, four, or five values, or Visual Analogue Scales (VAS) with a range 0–100. VAS scales often need to be downsized and discretized using intervals or clusters. Cutoff points for these intervals/clusters need to be carefully selected and justified. Our objective was to underline the importan...


Bone mineral density and body composition among individuals who practice sports...

Pinheiro, João; Ribeiro, Luís Pedro; Coelho-e-Silva, Manuel

The purpose of this study was to evaluate indicators of bone health associated with sports practice in male adolescents using dual-energy X-ray absorptiometry (DXA) to measure bone mineral content (BMC), density (BMD), and body composition (BC) for the whole body (WB) and specific regions. This cross-sectional study involved 65 individuals (18–35 years). Athletes had higher BMD for WB (1.064 ± 0.121 g/m−2) than...


Functional assessment for discharge planning in a Convalescence Unit

Luísa Catarina Barbosa Cardoso, Luísa Cardoso; Pocinho, Margarida; Pinheiro, João

Introdução: A funcionalidade é o conceito mais importante na reabilitação dos utilizadores de uma Unidade de Convalescença (UC). Ao final dos 30 dias de internação, os indivíduos chegam alta para suas residências ou devem ser avaliados a necessidade de outro tipo de resposta. Objetivos: É importante avaliar se o nível funcional no momento da alta da unidade pode prever resultados e determinar o destino dos indi...


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