8 documents found, page 1 of 1

High VEGFA expression Is associated with improved progression-free survival aft...

Glioblastoma (GB) is a deadly tumor that demands for relevant biomarkers, particularly regarding patients’ response to treatment. MMP-2, MMP-9, VEGFA, and YKL40 are important molecules, given their implication in the infiltrative and angiogenic phenotype of GBs. The purpose of this study was to assess the relationship between the expression of MMP-2, MMP-9, VEGFA, and YKL40 in GB tissues and the patients’ respo...

Generational accounting in Portugal : an assessment of long-term fiscal sustain...

The social and economic developments in European countries have put pressure on their national budgets and threaten the sustainability of public policies. The traditional fiscal indicators, specifically, the deficit and the debt, which are still used today as guiding tools, have proved to be insufficient, due to their arbitrary nature and short-term focus. In this paper, we resort to an alternative fiscal indic...

A 30-year long-term experience in appendix neuroendocrine neoplasms—granting a ...

Neuroendocrine neoplasms (NENs) are the most common tumor of the appendix and have an excellent prognosis. Appendiceal tumors diagnosed between 1989 and 2019 were reviewed, and clinical data were collected from patient files. Part of the series was immuno-profiled for markers related to cell cycle proliferation and/or senescence-type, apoptotic, and metastatic potential. Appendix NENs were detected in 74 patien...

Histological Subtypes and Clinical Behavior Evaluation of Salivary Gland Tumors

Introduction: Salivary gland tumors include a wide spectrum of histological subtypes and clinical behavior, which we aim to evaluate.Material and Methods: We performed a retrospective study of all salivary gland tumors diagnosed and treated at the Centro Hospitalar São João, Porto, between 2005 and 2015. Histological re- evaluation was performed in all cases and patient files were reviewed and both clinical and...

Parona Space Abscess Derived from Dental Disease: Multidisciplinary Approach

Parona Space infection is a rare forearm condition. We present a case of a 55-year-old male with pain and loss of function in the distal forearm for one week, with no previous history of trauma. Additionally, he presented a history of odontogenic infection, synchronous with the onset of the symptoms in the forearm, with spontaneous resolution. The wrist ultrasound found an abscess in the Parona space that was s...

TERT promoter mutations in pancreatic endocrine tumours are rare and mainly fou...

One of the hallmarks of cancer is its unlimited replicative potential that needs a compensatory mechanism for the consequential telomere erosion. Telomerase promoter (TERTp) mutations were recently reported as a novel mechanism for telomerase re-activation/expression in order to maintain telomere length. Pancreatic endocrine tumors (PETs) were so far recognized to rely mainly on the alternative lengthening of t...

O conhecimento do passado para apoiar, no futuro, a Agricultura, Zootecnia e Te...

Using ATLANTIS - Tierra 2.0 and GIS environmental information to predict the sp...

O conhecimento da distribuição de espécies raras requer muito esforço devido às dificuldades inerentes à detecção das suas populações. Neste capítulo, apresenta-se um exemplo de modelação da distribuição potencial de espécies endémicas de insectos, que constituem uma preocupação de conservação nos Açores. São analisados dados extraídos da base de dados ATLANTIS com o objectivo de desenvolver mapas preditivos da...