26 documents found, page 1 of 3
The impact of positive childhood experiences: A systematic review focused on ch...
Sousa, Marta; Machado, Ana Beatriz; Pinheiro, Marina; Pereira, Bárbara; Caridade, Sónia; Almeida, Telma Catarina; Cruz, Ana Rita; Cunha, OlgaChildhood and adolescence are crucial stages of life, characterized by significant changes that profoundly influence overall development. While positive childhood experiences (PCEs) can help mitigate the effects of adverse events during these formative years, they have not been as thoroughly researched. Then, this systematic review aims to address this gap by organizing the existing literature on PCEs and exami...
The impact of positive childhood experiences: a systematic review focused on ch...
Sousa, Marta; Machado, Ana Beatriz; Pinheiro, Marina; Pereira, Bárbara; Caridade, Sónia Maria Martins; Almeida, Telma Catarina; Cruz, Ana RitaChildhood and adolescence are crucial stages of life, characterized by significant changes that profoundly influence overall development. While positive childhood experiences (PCEs) can help mitigate the effects of adverse events during these formative years, they have not been as thoroughly researched. Then, this systematic review aims to address this gap by organizing the existing literature on PCEs and exami...
Psychopathy and violent offenses: a comparison between incarcerated men and wom...
Cunha, Olga Cecília Soares; Pinheiro, Marina; Conde, Ana RitaResearch suggests psychopathic traits may differ by gender, yet comparative studies are limited. This study compared Portuguese incarcerated men and women on psychopathy and examined whether psychopathy and its facets are associated with violent offenses. A total of 131 men and 63 women were assessed with the Revised Psychopathy Checklist (PCL-R). Men scored higher on total psychopathy, interpersonal, and affec...
Positive childhood experiences and adult outcomes: A systematic review
Cunha, Olga; Sousa, Marta; Pereira, Bárbara; Pinheiro, Marina; Machado, Ana Beatriz; Caridade, S.; Almeida, TelmaAlthough positive childhood experiences (PCEs) may serve as protective factors against the negative consequences of childhood adversity, they have been less extensively studied. However, more recently, there has been a growing interest in understanding the role of these experiences. This systematic review aims to address this research gap by systematizing the existing literature on PCEs and examining their rela...
Positive childhood experiences and adult outcomes: A systematic review
Cunha, Olga Cecília Soares; Sousa, Marta; Ferreira, Bárbara; Pinheiro, Marina; Machado, Ana Beatriz; Caridade, Sónia Maria MartinsAlthough positive childhood experiences (PCEs) may serve as protective factors against the negative consequences of childhood adversity, they have been less extensively studied. However, more recently, there has been a growing interest in understanding the role of these experiences. This systematic review aims to address this research gap by systematizing the existing literature on PCEs and examining their rela...
Disseminated tuberculosis in an infant – Case report
Abreu, Ana Margarida; Miranda, Sofia; Carvalho, Isabel; Gonçalves, Augusta; Branco, Liliana; Barros, Daniela; Pinheiro, MarinaInfants are a particularly vulnerable group for the development of severe and/or extrapulmonary forms of tuberculosis. The difficulty in establishing a definitive and timely diagnosis contributes to the high morbimortality in this age group. Investigation often relies on a high index of suspicion. Herein is reported a case of disseminated tuberculosis in an infant that highlights its clinical complexity and dia...
R2CHA2DS2-VA predictsthe cardiovascular risk after carotid endarterectomy
Quesado, João; Dias, Lara; Pereira-Macedo, Juliana; Duarte-Gamas, Luís; Khairy, Ahmed; Pinheiro, Marina; Reis, Pedro; Andrade, José P.Background: R2CHA2DS2-VA score has been used to predict short and long-term outcomes in many cardiovascular diseases. This study aims to validate the R2CHA2DS2-VA score as a long-term major adverse cardiovascular events (MACE) predictor after carotid endarterectomy (CEA). Secondary outcomes were also assessed regarding the incidence of all-cause mortality, acute myocardial infarction (AMI), major adverse limb e...
Serine-based surfactants as effective antimicrobial agents against multiresista...
Silva, Sandra G.; Pinheiro, Marina; Pereira, Rui; Dias, Ana Rita; Ferraz, Ricardo; Prudêncio, Cristina; Eaton, Peter J.; Reis, SaletteThe antimicrobial activity of two serine derived gemini cationic surfactants, amide (12Ser)2CON12 and ester (12Ser)2COO12, was tested using sensitive, E. coli ATCC 25922 and S. aureus ATCC 6538, and resistant, E. coli CTX M2, E. coli TEM CTX M9 and S. aureus ATCC 6538 and S. aureus MRSA ATCC 43300 Gram-positive and Gram-negative bacteria strains. Very low MIC values (5 μM) were found for the two resistant strai...
Nanomedicine for the delivery of RNA in cancer
Ghidini, Michele; Silva, Sandra G.; Evangelista, Jessica; Vale, Maria Luísa C. do; Farooqi, Ammad Ahmad; Pinheiro, MarinaThe complexity, and the diversity of the different types of cancers allied to the tendency to form metastasis make treatment efficiency so tricky and often impossible due to the advanced stage of the disease in the diagnosis. In recent years, due to tremendous scientific breakthroughs, we have witnessed exponential growth in the elucidation of mechanisms that underlie carcinogenesis and metastasis. The developm...
MANAGEMENT OF THE UPPER LIMB ARTERIOVENOUS MALFORMATIONS
Pinheiro, Marina; Carreira, Mariana; Rocha-Neves, JoãoArteriovenous malformations (AVMs) involving the upper limb constitute 10% of the total AVMs. In the upper limb, AVMs are more frequent in the hand than in the arm, being the hand one of the body’s regions more frequently associated with AVMs, coming after the head and neck. The total prevalence of the upper limb AVMs remains unknown and there is currently no definitive consensus for the treatment of upper limb...