METHOD VALIDATION FOR HS-SPME / GC-MS FOR DETERMINATION OF CARBARYL IN BLOOD PLASMA. The aim this research is to develop a HS-SPME/GC–MS method to analyze the carbaryl in blood plasma samples of the rural workers, who live round the perimeter of Chapada do Apodi-CE. This was achieved by chromatographic signal of the 1-naftol, degradation product of carbaryl with the intention of evaluating the degree of exposur...
Objective To evaluate the expression of genes related to nuclear excision (ERCC8, XPA and XPC), homologous recombination and non-homologous end-joining (ATM, BRCA1, BRCA2 and LIG4) repair mechanisms, using quantitative PCR methodologies, and it relation with bone marrow cellularity in myelodysplastic syndrome (MDS). Methods and results A total of 51 adult de novo patients with MDS (3 refractory anaemia (RA), 11...