49 documents found, page 1 of 5

A matter of non-matter: an editorial

List of contributors

Acknowledgements

A matter of non-matter: an editorial

Methylphenidate-induced dyskinesia, an underrecognized adverse effect In ADHD t...

Attention deficit hyperactivity disorder (ADHD) is one of the leading mental and behavioral disorders in childhood and adolescence and remains a clinical challenge for healthcare professionals. Methylphenidate (MPH) is the first-line pharmacological treatment option for children over six years of age, but it is not without side effects. While the most common are mild and reversible upon therapy discontinuation,...

Image-guided nanodelivery of Pt(IV) prodrugs to GRP-receptor positive tumors

Over the last decades, gold nanoparticles (AuNPs) have proven to be remarkable tools for drug delivery and theranostic applications in cancer treatment. On the other hand, Pt(IV) prodrugs have been employed as an interesting alternative to the more common Pt(II) complexes, such as cisplatin, for cancer chemotherapy. Searching to design an image-guided nanocarrier to deliver selectively Pt(IV) prodrugs to tumors...

Antitumoral and antimicrobial activities of block copolymer micelles containing...

Gold(III) bisdithiolate complexes have been reported as potential antimicrobial and antitumoral agents. The complex [Au(cdc)2]− (cdc=cyanodithioimido carbonate) displayed antimicrobial and outstanding antitumor activity against the ovarian cancer cells A2780 and A2780cisR, which are sensitive and resistant to cisplatin, respectively. However, poor water solubility may hamper its clinical use. Block copolymer mi...

Idiopathic Spinal Cord Herniation - An Extremely Rare Cause of Paraparesis: Cas...

Idiopathic spinal cord herniation is a rare disorder, consisting of a ventral displacement of the spinal cord through a dural defect. The resulting adhesion and vascular compromise lead to neurological impairment. We report the case of a 54yearold male, with a previous urological surgery resulting in chronic vesical catheterization, with a worsening paraparesis associated with anesthesia below T10. The magnetic...

Acute Campylobacter spp. gastroenteritis in the Pediatric Emergency Department ...

Introduction: Campylobacter spp. is the main cause of pediatric acute bacterial gastroenteritis (ABG) in the European Union, with greater incidence in children under five years old. Most patients present complete recovery within days of infection, with no associated comorbidities. Antibiotic therapy should be reserved for severe cases. Objectives: The aim of this study was to investigate the epidemiology, sympt...

Acute Campylobacter spp. gastroenteritis in the Pediatric Emergency Department ...

Introduction: Campylobacter spp. is the main cause of pediatric acute bacterial gastroenteritis (ABG) in the European Union, with greater incidence in children under five years old. Most patients present complete recovery within days of infection, with no associated comorbidities. Antibiotic therapy should be reserved for severe cases. Objectives: The aim of this study was to investigate the epidemiology, sympt...