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Effect of farnesol on growth, ergosterol biosynthesis, and cell permeability in...

Caetano, Erica Pacheco; Brilhante, Raimunda Sâmia Nogueira; Lima, Rita Amanda Chaves de; Leite, João Jaime Giffoni

Coccidioidomycosis is a systemic mycosis caused by the dimorphic fungi Coccidioides spp. The treatment for chronic and/or disseminated coccidioidomycosis can be prolonged and complicated. Therefore, the search for new drugs is necessary. Farnesol is a precursor in the sterol biosynthesis pathway that has been shown to present antifungal activity. Thus, the objective of this study was to evaluate the in vitro an...

Date: 2013   |   Origin: Oasisbr
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