3 documents found, page 1 of 1
Cholesterol Functionalized Nanoparticles Are Effective against Helicobacter pyl...
Pinho, AS; Pereira, R; Pereira, M; Rai, A; Ferreira, L; Martins, MCL; Parreira, PHelicobacter pylori chronic infection is the highest risk factor for the development of gastric cancer, being this Gram-negative bacterium classified as carcinogenic. The mounting resistance of H. pylori to antibiotics calls for innovative therapeutic strategies. Here, the proof-of-concept studies that support the development of a "trojan horse" therapeutic strategy based on cholesterol-grafted nanoparticles (C...
Paving the way for a non‐antibiotic and microbiota friendly therapy for Helicob...
Seabra, CL; Pinho, AS; Nunes, C; Amorim, I; Pedro, N; Henriques, P; Monteiro, C; Gomes, J; Machado, C; Gartner, F; Pereira, L; Reis, S; Reis, CABackground: The World Health Organization has identified Helicobacter pylori, a Gram-negative bacterium responsible for several gastric disorders, as one of the pathogenic bacteria that requires newer non-antibiotic approaches for its management. We previously demonstrated that nanostructured lipid carriers (NLC) loaded with docosahexaenoic acid (DHA-NLC)have excellent in vitro performance against H. pylori. Ma...
Exploring innovative adhesive approaches to manage medical adhesive-related ski...
Fialho, L; Albuquerque, J; Pinho, AS; Pereira, AM; Monteiro, C; Oliveira, N; Ferreira, S; Martins, MCLMedical adhesives are essential to secure wound care dressings and medical devices to the skin, to bind wound edges, track vital signs, or even provide local drug delivery. Despite several options in the market, most medical adhesives are composed of acrylate, hydrocolloid, and silicone, materials that are associated with the development of Medical Adhesive-Related Skin Injury (MARSI). Moreover, these injuries ...