8 documents found, page 1 of 1
Programmes Addressed to Informal Caregivers’ Needs: A Systematic Literature Rev...
Gemito, L; Alves, Elisabete; Moreira, J; Marques, MF; Caldeira, E; Ferreira, R; Bico, I; Pinho, L; Fonseca, C; Sousa, L; Lopes, MBackground: Addressing informal caregivers' needs is essential for ensuring quality healthcare and promoting citizen-centred care. This systematic review assessed current knowledge about programmes aimed at meeting the needs of informal caregivers of adults who are dependent on others for daily life activities. Methods: Following the PRISMA guidelines, the electronic databases EBSCOhost Research Platform, MEDLI...
Functional capacity of institutionalized older people and their quality of life...
Cano, F; Alves, Elisabete; Pinho, L; Fonseca, CésarBackground: The increasing number of institutionalized older individuals worldwide stresses the need to evaluate the association between the functional profile of institutionalized older adults and their quality of life (QoL), depressive symptoms and feelings of loneliness. Methods: A cross-sectional study was conducted in 19 residential facilities in Alentejo, Portugal. Between March and September 2023, all in...
The adaptive immune landscape of the colorectal adenoma–carcinoma sequence
Freitas, JA; Gullo, I; Garcia, D; Miranda, S; Spaans, L; Pinho, L; Reis, J; Sousa, F; Baptista, M; Resende, C; Leitão, D; Durães, C; Costa, JLBackground. The tumor immune microenvironment exerts a pivotal influence in tumor initiation and progression. The aim of this study was to analyze the immune context of sporadic and familial adenomatous polyposis (FAP) lesions along the colorectal adenoma–carcinoma sequence (ACS). Methods. We analyzed immune cell counts (CD3+, CD4+, CD8+, Foxp3+, and CD57+), tumor mutation burden (TMB), MHC-I expression and PD-...
Collagen type IV-related nephropathies in Portugal: pathogenic COL4A5 mutations...
Sá, MJ; Storey, H; Flinter, F; Nagel, M; Sampaio, S; Castro, R; Araújo, JA; Gaspar, MA; Soares, C; Oliveira, A; Henriques, AC; Costa, AG; Abreu, CPPathogenic mutations in genes COL4A3/COL4A4 are responsible for autosomal Alport syndrome (AS) and thin basement membrane nephropathy (TBMN). We used Sanger sequencing to analyze all exons and splice site regions of COL4A3/COL4A4, in 40 unrelated Portuguese probands with clinical suspicion of AS/TBMN. To assess genotype-phenotype correlations, we compared clinically relevant phenotypes/outcomes between homozygo...
Infeções associadas aos cuidados de saúde numa Unidade de Cuidados Intensivos N...
Pinho, L; Pinto, J; Braga, AC; Gouveia, S; Matos, L; Pombeiro, J; Almeida, ARESUMO Introdução: Os recém-nascidos (RN) internados em unidades de cuidados intensivos (UCIN) apresentam um risco acrescido de infeções associadas aos cuidados de saúde (IACS). Na Maternidade Júlio Dinis (MJD), após ter sido constatada uma incidência elevada de IACS, efetuaram-se alterações na prática clínica diária. Objetivos: Avaliar a eficácia das estratégias de prevenção de infeção implementadas na UCIN da...
Alcohol consumption among patients with hepatitis B infection in northern Portu...
Mota, A; Guedes, F; Areias, J; Pinho, L; Cardoso, MFAlcohol abuse is an important public health problem. In Portugal with a population of 10 millions of inhabitants, there are around 10% of alcoholics or excessive alcohol drinkers and 1% of chronically infected patients with hepatitis B virus (HBV). To examine the characteristics of patients with higher levels of alcohol consumption and to investigate the association between alcohol consumption and liver damage ...
Have you ever listened coastal inhabitants? Know what they think…
Martins, F; Almeida, A Betâmio De; Pinho, LCoastal dynamics changes, caused by natural or man-made factors, can to give rise serious consequences, namely at urban areas, exposing coastal population at risk. In this context, the understanding of the way people perceive the coastal dynamics and their exposure to risk is essential for the land use management and Integrated Coastal Zone Management. To get the perception of coastal population, this research ...
Epidemiological study of genotypes of hepatitis B virus in northern Portugal
Mota, A; Guedes, F; Areias, J; Pinho, L; Cardoso, MFWhile the overall prevalence of hepatitis B virus (HBV) infection in Portugal is around 1%, there are no published studies examining HBV genotypes in this country. This study aimed to survey HBV genotypes in the northern Portugal and to examine the possible associations between genotypes and gender, viral transmission routes, viral markers, viral load, and biochemical tests of liver function. The study sample c...