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Solubilization and hydrolysis of porcine coagulated blood protein using sub-cri...

Marques, Bianca; Nunes, Rafaela; Araújo-Rodrigues, Helena; Pintado, Manuela; Pereira, Ricardo N.; Teixeira, José A.; Rocha, Cristina M. R.

Pork represents a major fraction of the meat consumed worldwide but only 30% of the blood generated in slaughterhouses is re-used as raw material for food and feed. Innovative technologies and efficient processing strategies capable of generating added-value products from it are now attracting attention. In this study, the hydrolysis of porcine coagulated blood using sub-critical solvent extraction was investig...


Fire-resistant bio-based polyurethane foams designed with two by-products deriv...

Capêto, Ana Paula; Amorim, Manuela; Sousa, Sérgio; Costa, Joana R.; Uribe, Braian; Guimarães, Ana Sofia; Pintado, Manuela; Oliveira, Ana L. S.

There is a growing interest in replacing conventional fossil-based polymers and composites with waste-based materials and fillers for environmental sustainability. This study designed water-blown polyurethane rigid foams using two by-products from the Amyris fermentation process of producing β-farnesene. The distillation residue (FDR) served as the main polyol component in the foam’s formulation (PF), supplemen...


Methods for the collection of fish mucus: a systematic review

Cunha, Marta Fernandez; Coscueta, Ezequiel R.; Brassesco, María Emilia; Almada, Frederico; Gonçalves, David; Pintado, Manuela

The aquatic environment holds a vast source of organisms that provide numerous opportunities to bioprospect new molecules. Notably, fish are producers of an epidermal mucus that offers protection against pathogens, making it a promising source of bioactive molecules. This source of molecules, however, has yet to be thoroughly explored, and particularly, optimization of methods for collection and study is needed...


Fucoidans: exploring its neuroprotective mechanisms and therapeutic application...

Batista, Patrícia; Cunha, Sara A.; Ribeiro, Tânia; Borges, Sandra; Baptista-Silva, Sara; Oliveira-Silva, Patrícia; Pintado, Manuela

Background: Marine-derived natural products have been attracting attention from both the food and pharmaceutical sectors due to their promising therapeutic attributes. Algae and their biomolecules are examples of marine-derived products for ongoing research endeavors. Fucoidan, an algae-derived polysaccharide, has emerged as a recent biomolecule related to a diverse array of beneficial properties, with particul...


Anti-aging potential of a novel ingredient derived from sugarcane straw extract...

Carvalho, Maria João; Pedrosa, Sílvia Santos; Mendes, Adélia; Azevedo-Silva, João; Fernandes, João; Pintado, Manuela; Oliveira, Ana L. S.

Natural and sustainable anti-aging ingredients have gained attention from the cosmetic industry. This study evaluated the anti-aging potential of a sugarcane straw extract-based (SSE) cosmetic ingredient. First, cytotoxicity tests were assessed in keratinocytes and fibroblast cell lines, and sensitization was carried out through the direct peptide reactivity assay. Subsequently, various anti-aging properties we...


Antimicrobial chitosan/TPP-based coatings for the prevention of biodeterioratio...

Silva, Nádia C.; Castro, Diana; Neto, Cláudia; Madureira, Ana Raquel; Pintado, Manuela; Moreira, Patrícia R.

Outdoor stone sculptures are prone to accelerated deterioration caused by the proliferation of microorganisms in the stone. The physical, chemical and mechanical action of microorganisms on stone heritage causes aesthetic and structural changes that devalue the artworks over time. Developing more sustainable and ecological alternatives for their preventive conservation is necessary to reduce the negative enviro...


Impact of washing and freezing on nutritional composition, bioactive compounds,...

Marçal, Sara; Sousa, Sérgio; Araújo-Rodrigues, Helena; Silva, Inês V.; Campos, Débora A.; Pintado, Manuela

Mango peels are widely produced and highly perishable. Disinfectant washing and freezing are among the most used methods to preserve foods. However, their impact on products’ properties is conditioned by the foods’ features. This study evaluated for the first time the phytochemical composition, antioxidant activity, and microstructure of mango peels washed with peracetic acid (27 mg/mL for 19 min) and frozen at...


Effect of blueberry supplementation on a diet-induced rat model of prediabetes—...

Ferreira, Gonçalo; Vieira, Pedro; Alves, André; Nunes, Sara; Preguiça, Inês; Martins-Marques, Tânia; Ribeiro, Tânia; Girão, Henrique; Figueirinha, Artur

Blueberries, red fruits enriched in polyphenols and fibers, are envisaged as a promising nutraceutical intervention in a plethora of metabolic diseases. Prediabetes, an intermediate state between normal glucose tolerance and type 2 diabetes, fuels the development of complications, including hepatic steatosis. In previous work, we have demonstrated that blueberry juice (BJ) supplementation benefits glycemic cont...


Hesperidin from orange peel as a promising skincare bioactive: an overview

Rodrigues, Cristina V.; Pintado, Manuela

The pursuit for better skin health, driven by collective and individual perceptions, has led to the demand for sustainable skincare products. Environmental factors and lifestyle choices can accelerate skin aging, causing issues like inflammation, wrinkles, elasticity loss, hyperpigmentation, and dryness. The skincare industry is innovating to meet consumers’ requests for cleaner and natural options. Simultaneou...


Egyptian citrus essential oils recovered from lemon, orange, and mandarin peels...

Ibrahim, Faten Mohamed; Mohammed, Reda Sayed; Abdelsalam, Eman; Ashour, Wedian El-Sayed; Magalhães, Daniela; Pintado, Manuela; Habbasha, El Sayed El

Citrus peels are an important by-product of citrus processing industries, but a large part is considered waste. There has been increased attention in the last five years on these industrial by-products, especially those containing residual essential oils (EOs). Lemon, orange, and mandarin peels from Egypt were subjected to hydro-distillation to obtain EOs, which were analyzed via mass spectrometry (GC/MS) and b...


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