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Probe-based metagenomic pathogen detection

Ferreira, Rita; Coelho, Luís; Santos, João Dourado; Sobral, Daniel; Isidro, Joana; Mixão, Verónica; Pinto, Miguel; Nunes, Alexandra; Borrego, Maria José

Publisher Copyright: Copyright © 2025 Ferreira, Coelho, Santos, Sobral, Isidro, Mixão, Pinto, Nunes, Borrego, Lopo, Oleastro, Sousa, Palminha, Veríssimo, Gargaté, Guiomar, Cordeiro, Macedo, Bajanca-Lavado, Paixão, Duarte, Vieira, Borges and Gomes.; Probe-based pathogen enrichment, followed by NGS, is a promising tool for complex diagnosis, overcoming traditional challenges of shotgun metagenomics, namely small ...


Genome-scale analysis of Mycobacterium avium complex isolates from Portugal rev...

Carneiro, Sofia; Pinto, Miguel; Rodrigues, Joana; Gomes, João Paulo; Macedo, Rita

Health Emergency Preparedness and Response (HERA) project - European Commission - Grant/2021/PHF/23776. European Union (EU) - EU4H-2022-DGAMS-IBA-1. Publisher Copyright: © 2024 The Authors. Published by Elsevier B.V.; Opportunist infections caused by nontuberculous mycobacteria (NTM) have emerged as a significant public health problem. Among these, species of the Mycobacterium avium complex (MAC) are the main r...


Microevolution of a Mycobacteroides abscessus subsp. bolletii strain in a clini...

Santos, Andrea; Pinto, Miguel; Carneiro, Sofia; Silva, Sónia; Rodrigues, Irene; Munhá, João; Gomes, João Paulo; Macedo, Rita

Publisher Copyright: © 2023 The Authors; Mycobacteroides abscessus complex (MAB), a fast-growing nontuberculous mycobacterium, is emerging as a significant infectious disease threat, due to both intrinsic and acquired resistance mechanisms to antibiotics and disinfectants and the need for extensive and multidrug regimens for treatment. Despite the prolonged regimens, outcomes are poor and persistence cases have...


Comparative complete scheme and booster effectiveness of COVID-19 vaccines in p...

Kislaya, Irina; Peralta-Santos, André; Borges, Vítor; Vieira, Luís; Sousa, Carlos; Ferreira, Bibiana; Pelerito, Ana; Gomes, João Paulo

Funding Information: The acquisition of sequencing equipment and reagents used in this study by the Instituto Nacional de Saúde Doutor Ricardo Jorge was partially funded by the HERA project (grant no. 2021/PHF/23776), supported by the European Commission through the European Centre for Disease Control, and also partially funded by the Genome PT project (grant no. POCI‐01‐0145‐FEDER‐022184), supported by COMPETE...


Genome-Scale Characterization of Mycobacterium abscessus Complex Isolates from ...

Carneiro, Sofia; Pinto, Miguel; Silva, Sónia; Santos, Andrea; Rodrigues, Irene; Santos, Daniela; Duarte, Sílvia; Vieira, Luís; Gomes, João Paulo

The acquisition of equipment for whole-genome sequencing used in this study was funded by the HERA (Human and Environmental Risk Assessment) project (Grant/2021/PHF/23776) supported by the European Commission through the European Centre for Disease Prevention and Control (ECDC). This work was also partially funded by the GenomePT project (POCI-01-0145-FEDER-022184) supported by COMPETE 2020 (Operational Program...


Neisseria gonorrhoeae clustering to reveal major European whole-genome-sequenci...

Pinto, Miguel; Borges, Vítor; Isidro, Joana; Rodrigues, João Carlos; Vieira, Luís; Borrego, Maria José; Gomes, João Paulo

Funding information M.P. was supported by the Portuguese Science and Technology Foundation (FCT) through grant SFRH/BD/109264/2015. This work was partially funded by the GenomePT project (POCI-01-0145-FEDER-022184), supported by COMPETE 2020 – Operational Programme for Competitiveness and Internationalisation (POCI), Lisboa Portugal Regional Operational Programme (Lisboa2020), Algarve Portugal Regional Operatio...


Multidrug-Resistant Salmonella enterica Serovar Rissen Clusters Detected in Azo...

Silveira, Leonor; Pinto, Miguel; Isidro, Joana; Pista, Ângela; Themudo, Patrícia; Vieira, Luís; Machado, Jorge; Gomes, João Paulo

Gastrointestinal infections caused by nontyphoidal Salmonella (NTS) remain one of the main causes of foodborne illness worldwide. Within the multiple existing Salmonella enterica serovars, the serovar Rissen is rarely reported, particularly as a cause of human salmonellosis. Between 2015 and 2017, the Portuguese National Reference Laboratory of Gastrointestinal Infections observed an increase in the number of c...


Letter to the Editor: Medication-Overuse Headache is Common in Portuguese Migra...

Duarte Mendonça, Marcelo; Caetano, André; Salavisa, Manuel; Viana-Baptista, Miguel; Miguel, Rita; Pinto, Miguel; Barbosa, Raquel; Ladeira, Filipa

Carta ao Editor: A Cefaleia por Uso Excessivo de Medicação é Comum em Doentes Portugueses com Enxaqueca


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