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Spectrum of ankylosing spondylitis in Portugal. Development of BASDAI, BASFI, B...

M. Pimentel-Santos, F.; Mourão, Ana Filipa; Ribeiro, Célia; Costa, J. A.; Santos, Helena; Barcelos, A.; Pinto, Patricia; Godinho, F.; Cruz, Margarida

The availability of population-specific normative data regarding disease severity measures is essential for patient assessment. The goals of the current study were to characterize the pattern of ankylosing spondylitis (AS) in Portuguese patients and to develop reference centile charts for BASDAI, BASFI, BASMI and mSASSS, the most widely used assessment tools in AS. AS cases were recruited from hospital outpatie...


Whole blood transcriptional profiling in ankylosing spondylitis identifies nove...

M. Pimentel-Santos, F.; Ligeiro, Dário; Matos, Mafalda; Mourão, Ana F.; Costa, José; Santos, Helena; Barcelos, Anabela; Godinho, Fátima; Pinto, Patricia

Introduction: A number of genetic-association studies have identified genes contributing to ankylosing spondylitis (AS) susceptibility but such approaches provide little information as to the gene activity changes occurring during the disease process. Transcriptional profiling generates a 'snapshot' of the sampled cells' activity and thus can provide insights into the molecular processes driving the disease pro...


Guia prático de utilização de terapêuticas de biotecnologia na artrite reumatóide

Fonseca, Joao Eurico; Canas Silva, J. A.; Canhão, Helena; Santos, Maria Jose; Barcelos, Anabela; Ines, Luis; Costa, Maria Lucia; Rodrigues, Mario


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