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In vitro trypanocidal evaluation of pinane derivatives from essential oils of r...
Sartorelli, Patricia; Santana, Jefferson S.; Guadagnin, Rafael C.; Lago, João Henrique G.; Pinto, Érika G.; Tempone, André G.; Stefani, Hélio A.Essential oils of ripe fruits from Schinus terebinthifolius (Anacardiaceae), obtained using a pilot extractor and a Clevenger apparatus were chemically characterized. Due the high amount of (-)- α-pinene in both oils, this monoterpene was tested against the protozoan parasite Trypanosoma cruzi, showing a moderate potential (IC50 63.56 µg/mL) when compared to benznidazole (IC50 43.14 µg/mL). Otherwise, (-)- α-pi...
Date: 2018
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Origin: Oasisbr