Cloud Computing is widely recognized as a recent computing paradigm of digital transformation, in which scalable and elastic computational resources are delivered as a service through internet technologies. Understanding the impacts of the Cloud model on how companies organize their processes is essential. This study aims to investigate the main impacts of the Cloud Computing model on the processes within the I...
This article explores the conditions under which unions achieve inclusive outcomes for nonstandard workers in their collective agreements. Using fsQCA, it compares 52 collective agreements signed in Portugal between 2003 and 2019. Additionally, it reports on three short case studies. Results show that the unions’ potential to mobilize resources in favour of outsiders is crucial and is due to either high union d...
This paper tackles the problem of detecting emerging words on a language, based on social networks content. It proposes an approach for detecting new words on Twitter, and reports the achieved results for a collection of 8 million Portuguese tweets. This study uses geolocated tweets, collected between January 2018 and June 2019, and written in the Portuguese territory. The first six months of the data were used...
Introduction Osteoarthritis (OA) is one of the main reasons for early retirement of sport horses and despite new technologies, radiographic examination is still the most commonly used method of diagnosis. Radiographic changes due to OA in horses are mainly found in the distal limb and tarsal joints (Baccarin et al., 2012). The objectives of the present study were to identify the most frequent radiological findi...
O diagnóstico de claudicações em equino, nomeadamente causada por doença articular, é um dos motivos mais frequentes de chamada do médico veterinário e uma das causas mais comuns de retirada dos cavalos de competição. No entanto, o diagnóstico desta afeção é muitas vezes feito baseado em metodologias subjetivas, que dificultam a avaliação da resposta à terapia e o estabelecimento de um prognóstico. Neste projet...
Introdução e objetivos A avaliação radiológica do sistema locomotor faz atualmente parte da avaliação de rotina em equinos, com o objetivo de diagnosticar alterações que possam comprometer a vida desportiva do cavalo. Presentemente existem alguns estudos sobre os achados radiográficos em cavalos de desporto, sendo que, os mais comuns são relacionados com a presença de osteoartrite (OA). O objetivo deste estudo ...
Glioblastoma (GBM) is a universally fatal brain cancer, for which novel therapies targeting specific underlying oncogenic events are urgently needed. While the WNT pathway has been shown to be frequently activated in GBM, constituting a potential therapeutic target, the relevance of WNT6, an activator of this pathway, remains unknown. Methods: WNT6 protein and mRNA levels were evaluated in GBM. WNT6 levels were...
In phenylketonuria (PKU), synthetic protein derived from L-amino acids (AAs) is essential in a low-phenylalanine (Phe) diet. Glycomacropeptide (GMP), an intact protein, is very low in Phe in its native form. It has been modified and adapted for PKU to provide an alternative protein source through supplementation with rate-limiting amino acids (GMP-AAs), although it still contains residual Phe. This review aims ...