8 documents found, page 1 of 1
Graphene oxide topical administration: Skin permeability studies
Silva, FALS; Costa-Almeida, R; Timochenco, L; Amaral, SI; Pinto, S; Gonçalves, IC; Fernandes, JR; Magalhães, FD; Sarmento, B; Pinto, AMNanostructured carriers have been widely used in pharmaceutical formulations for der-matological treatment. They offer targeted drug delivery, sustained release, improved biostability, and low toxicity, usually presenting advantages over conventional formulations. Due to its large surface area, small size and photothermal properties, graphene oxide (GO) has the potential to be used for such applications. Nanogr...
High-yield production of nano-lateral size graphene oxide by high-power ultraso...
Timochenco, L; Costa-Almeida, R; Bogas, D; Silva, FALS; Silva, J; Pereira, A; Magalhães, FD; Pinto, AMNanographene oxide (GOn) constitutes a nanomaterial of high value in the biomedical field. However, large scale production of highly stable aqueous dispersions of GOn is yet to be achieved. In this work, we explored high-power ultrasonication as a method to reduce particle size of GO and characterized the impact of the process on the physicochemical properties of the material. GOn was obtained with lateral dime...
Exposure of smaller and oxidized graphene on polyurethane surface improves its ...
Borges, I; Henriques, PC; Gomes, RN; Pinto, AM; Pestana, M; Magalhães, FD; Gonçalves, ICCatheter-related infections are a common worldwide health problem, highlighting the need for antimicrobial catheters. Here, antibacterial potential of graphene nanoplatelets (GNP) incorporated in the commonly used polymer for catheter manufacture—polyurethane (PU)—is investigated. Two strategies are explored: melt-blending, producing a composite, and dip coating, where a composite layer is deposited on top of P...
Near-infrared radiation-based mild photohyperthermia therapy of non-melanoma sk...
Costa-Almeida, R; Bogas, D; Fernandes, JR; Timochenco, L; Silva, FALS; Meneses, J; Gonçalves, IC; Magalhães, FD; Pinto, AMUsing a one-step thermal reduction and non-covalent chemical functionalization process, PEGylated reduced nanographene oxide (rGOn-PEG) was produced from nanographene oxide (GOn) and characterized in terms of particle size, dispersion stability, chemistry, and photothermal properties, in view of its use for photothermal therapy (PTT) of non-melanoma skin cancer. GOn infrared spectrum presented more intense band...
Erratum: Borges, I., et al. Exposure of Smaller and Oxidized Graphene on Polyur...
Borges, I; Henriques, PC; Gomes, RN; Pinto, AM; Pestana, M; Magalhães, FD; Gonçalves, ICThe authors wish to make the following corrections to this paper [1]: Funding: This research was funded by Fundação para a Ciência e a Tecnologia (FCT) and Fundo Europeu de Desenvolvimento Regional (FEDER) for Projects POCI-01-0145-FEDER-006939, POCI-01-0145-FEDER-007274, PTDC/CTM-BIO/4033/2014, and NORTE-01-0145-FEDER-000012, and projects UID/BIM/04293/2019—i3S and UIDB/00511/2020—LEPABE, funded by national fu...
Poly(lactic acid) composites containing carbon-based nanomaterials: A review
Gonçalves, C; Gonçalves, IC; Magalhães, F. D.; Pinto, AMPoly(lactic acid) (PLA) is a green alternative to petrochemical commodity plastics, used in packaging, agricultural products, disposable materials, textiles, and automotive composites. It is also approved by regulatory authorities for several biomedical applications. However, for some uses it is required that some of its properties be improved, namely in terms of thermo-mechanical and electrical performance. Th...
Preliminary results of an Acceptance and Commitment Therapy (ACT) brief group i...
Castilho, P; Pinto, AM; Viegas, R; Carvalho, S; Madeira, N; Martins, MJAcceptance and Commitment Therapy (ACT) is a contextual-behavioral therapy with promising results in various psychological disorders, including psychosis. This study aims to compare the potential benefits of a 4-session ACT group intervention with the interventions commonly offered in Portugal. ACT participants improved in a wider range of measures and 2 of the 3 patients improved significantly in both symptoms...
CD26/DPPIV and response to hepatitis B vaccination
Dourado, M; Alves, V; Mesquita, L; Ramos, I; Pinto, AM; Rosa, MSThe prevention of hepatitis B is important, since it is responsible for significant morbidity and mortality around the world. Unfortunately, hepatitis B vaccine does not always induce protective immunity. The lack of immune response to vaccine (non-responders) can depend on individual characteristics. The objective of this study was to correlate the CD26/DPPIV cellular expression and DPPIV serum activity with H...