3 documents found, page 1 of 1
Hepatitis B Virus Genotypes and Subgenotypes Circulating in Infected Residents ...
Silva, Carolina; Ramos, Diogo; Quina, Miriam; Pádua, ElizabethDespite the availability of a vaccine against hepatitis B virus (HBV), this infection still causes public health problems, particularly in susceptible populations. In Portugal, universal free vaccination started in 1994, and most HBV infections are diagnosed in immigrants from high-prevalence countries. Our aim was to assess the pattern of HBV genotypes/subgenotypes in samples collected between 2017 and 2021 fr...
Diversity of Human T-Lymphotropic Virus Type 1 Cosmopolitan Subtype (HTLV-1a) C...
Quina, Miriam; Ramos, Diogo; Silva, Carolina; Pádua, ElizabethHuman T-cell lymphotropic virus type 1 (HTLV-1) prevalence in Portugal is low and mainly affects immigrants from endemic areas where human immunodeficiency virus (HIV) infection represents a public health problem. Despite the majority of HTLV-1-infected individuals remains asymptomatic, severe pathologies may develop after prolonged viral persistence, namely an aggressive form of leukemia. An increased mortalit...
Looking at the Molecular Target of NS5A Inhibitors throughout a Population High...
Ramos, Diogo; Pinto, Miguel; Sousa Coutinho, Rodrigo; Silva, Carolina; Quina, Miriam; Gomes, João Paulo; Pádua, ElizabethHepatitis C virus (HCV) is associated with liver damage and an increased progression rate to cirrhosis and hepatocellular carcinoma. In Portugal, it is prevalent in vulnerable populations such as injection drug users (IDU). HCV is characterized by a high intra-host variability, and the selecting driving forces could select variants containing resistance-associated substitutions (RAS) that reduce treatment effec...